Does serum ferritin correlate with coronary angiography findings?

Autor: Paulo Caramori, Letícia Ribeiro, Luciana Kirschnick, Maria Luiza Brizolara, Cristiane Bauermann Leitão, Waldomiro Carlos Manfroi, Rafael Henriques Candiago, Rosana Cruz, Josiane de Souza, Karen Gomes Ordovas, Alcides José Zago, Juliana Ghisleni de Oliveira
Rok vydání: 1999
Předmět:
Zdroj: International Journal of Cardiology. 69:149-153
ISSN: 0167-5273
Popis: Background: A number of epidemiological studies have described a positive relationship between serum ferritin levels and coronary heart disease. In this prospective study, we evaluated the association between serum ferritin levels and the angiographic extent of coronary atherosclerosis. Method: We studied 307 consecutive patients (60.9% male, age 60.1±11.0 years) referred for diagnostic coronary angiography. Risk factors for coronary artery disease, lipids and ferritin levels, as well clinical characteristics were recorded from all patients. Two experienced cardiologists blinded for clinical and laboratory data reviewed the cinefilms. Angiographic significant coronary artery disease (CAD) was defined as any more than a 50% diameter stenosis. Results: From the 307 patients, 196 (63.8%) were found to have angiographic significant CAD. The presence of significant CAD was associated with ferritin levels (P=0.015) as well as patient age (P
Databáze: OpenAIRE