Effects of glycerol on cochlear frequency selectivity in patients with Menière's disease
| Autor: | René Dauman, George A. Tavartkiladze, Robert V. Harrison, Jean-Marie Aran |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Glycerol
medicine.medical_specialty Frequency selectivity business.industry Speech Intelligibility Action Potentials Electrocochleography Audiology medicine.disease Transtympanic electrocochleography Audiometry Evoked Response Cochlea MENIERE DISEASE Otorhinolaryngology Audiometry Medicine Humans In patient business Meniere Disease Meniere's disease |
| Zdroj: | The Journal of speech and hearing disorders. 50(2) |
| ISSN: | 0022-4677 |
| Popis: | During transtympanic electrocochleography, action potential (AP) tuning curves were derived as a measure of cochlear frequency selectivity. In 18 out of 21 patients with symptoms of Menière's disease, a poor frequency selectivity was observed. In 12 subjects the effects on frequency selectivity of oral glycerol were measured, and in 5 patients AP tuning curves indicated an improvement in sharpness of tuning by a factor of 1.5–2.5. These changes started approximately 30 min after oral glycerol administration. In 2 subjects there was a deterioration in AP tuning. In 5 patients no significant changes were observed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|