Chemical occlusion at the uterotubal junction in monkeys
| Autor: | Larry E. Seitz, Horace E. Thompson, Thomas S. Moulding, Charles A. Dafoe |
|---|---|
| Rok vydání: | 1972 |
| Předmět: |
Pathology
medicine.medical_specialty Polymers Sterilization Tubal Lumen (anatomy) Lesion chemistry.chemical_compound Formaldehyde Occlusion Methods medicine Animals Uterotubal junction Paraformaldehyde Fallopian Tubes Granuloma Ethanol business.industry Muscles Uterus Myometrium Obstetrics and Gynecology Population explosion Haplorhini Sclerosing Solutions medicine.anatomical_structure chemistry Macaca Female Rabbits medicine.symptom business Fallopian tube |
| Zdroj: | American Journal of Obstetrics and Gynecology. 113:388-393 |
| ISSN: | 0002-9378 |
| DOI: | 10.1016/0002-9378(72)90690-4 |
| Popis: | The current population explosion has stimulated interest in finding a simple transcervical approach to female sterilization. This experiment was designed to evaluate the potential of effecting tubal occlusion by producing a chronic lesion in the myometrium surrounding the lumen of the Fallopian tube. The method chosen was the injection of a chronic tissue irritant (paraformaldehyde) transcervically into the uterine cornua. Paraformaldehyde in aqueous suspension, with the use of various concentrations, was injected into the cornual area of monkey uteri. The histologic results were inconsistent and poor. Another group of monkeys was injected with paraformaldehyde suspended in absolute ethanol. This resulted in histologic evidence of an acute and chronic lesion in the myometrium in 90 per cent of the animals treated. The details and results of this experiment are described. The potential of using paraformaldehyde in an absolute ethanol suspension injected into the human uterine cornua as a means of producing permanent sterilization is discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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