Asymmetric total synthesis of (−)-deoxoprosophylline
| Autor: | Jieping Zhu, Angelique Jourdant |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
inorganic chemicals
chemistry.chemical_classification Stereochemistry organic chemicals Organic Chemistry Diol Total synthesis Biochemistry Aldehyde Reductive amination Serine chemistry.chemical_compound chemistry Intramolecular force Drug Discovery polycyclic compounds Organic chemistry heterocyclic compounds Deoxoprosophylline |
| Zdroj: | Tetrahedron Letters. 42:3431-3434 |
| ISSN: | 0040-4039 |
| DOI: | 10.1016/s0040-4039(01)00483-x |
| Popis: | Asymmetric syntheses of (-)-deoxoprosophylline from chiral L-N,N-dibenzyl serine (TBDMS) aldehyde is reported. A highly diastereoselective intramolecular reductive amination of ω-oxo amino diol is a key step of the present synthesis. © 2001 Elsevier Science Ltd. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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