Hospital-wide prospective mandatory surveillance of invasive aspergillosis in a French teaching hospital (2000–2002)

Autor: Marie Reine Mallaret, R. Grillot, D. Plantaz, J.P. Brion, C. Pinel, Christophe Pison, A. Fourneret-Vivier, Marie-Pierre Brenier-Pinchart, B. Lebeau, Frédéric Garban, Hervé Pelloux, R. Hamidfar
Přispěvatelé: Laboratoire Adaptation et pathogénie des micro-organismes [Grenoble] (LAPM), Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF), Laboratoire de Chimie Thérapeutique (UPRES-A CNRS 8076 BIOCIS), Université Paris-Sud - Paris 11 (UP11), Département de médecine aiguë spécialisée, CHU Grenoble-Hôpital Michallon
Rok vydání: 2006
Předmět:
Male
Pediatrics
Hospitalized patients
Consensus criteria
Aspergillosis
0302 clinical medicine
Epidemiology
MESH: Incidence
030212 general & internal medicine
Cross Infection
0303 health sciences
MESH: Middle Aged
Incidence
Incidence (epidemiology)
General Medicine
Middle Aged
MESH: Hematologic Diseases
3. Good health
Aspergillus
Infectious Diseases
Population Surveillance
MESH: Aspergillus
Female
France
Seasons
MESH: Hospital Units
Hospital Units
Microbiology (medical)
medicine.medical_specialty
Disease cluster
MESH: Population Surveillance
Teaching hospital
03 medical and health sciences
medicine
Humans
[SDV.BBM]Life Sciences [q-bio]/Biochemistry
Molecular Biology
MESH: Aspergillosis
Hospitals
Teaching
Intensive care medicine
Mycosis
MESH: Humans
030306 microbiology
business.industry
MESH: Cross Infection
MESH: Hospitals
Teaching
medicine.disease
Hematologic Diseases
MESH: Male
MESH: France
business
MESH: Seasons
MESH: Female
Zdroj: Journal of Hospital Infection
Journal of Hospital Infection, WB Saunders, 2006, 62 (1), pp.22-8. ⟨10.1016/j.jhin.2005.06.013⟩
ISSN: 0195-6701
Popis: A multidisciplinary working group devoted to epidemiological surveillance of invasive aspergillosis (IA) was created in January 2000 in Grenoble University Hospital. This article presents the results of a three-year IA surveillance. The multidisciplinary working group surveyed all hospitalized patients, and the mycology laboratory detected most suspected IA cases. Cases were reviewed monthly by the Aspergillosis Committee, and were classified according to international consensus criteria. Possible nosocomial acquisition was determined. Among the 490 alerts, 74 IA cases were observed: six proven cases (8%), 36 (49%) probable cases and 32 (43%) possible cases. The incidence was 4.4 (95% CI 3.4-5.4) IA/100 000 patient-days. Among the proven and probable IA cases, we observed 10 nosocomial cases and six cases of undetermined origin. No cases were noted in the protected rooms in the haematology unit. Only one cluster of cases (three nosocomial cases) was detected in the haematology unit. Forty-three percent of cases (N=32) were hospitalized in the haematology unit, and all other cases were hospitalized elsewhere. This three-year survey found a high rate of non-nosocomial IA cases and a high frequency of IA cases hospitalized in units other than haematology. Thus, this study shows the importance of IA surveillance in haematology units and all high-risk units.
Databáze: OpenAIRE
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