Hospital-wide prospective mandatory surveillance of invasive aspergillosis in a French teaching hospital (2000–2002)
Autor: | Marie Reine Mallaret, R. Grillot, D. Plantaz, J.P. Brion, C. Pinel, Christophe Pison, A. Fourneret-Vivier, Marie-Pierre Brenier-Pinchart, B. Lebeau, Frédéric Garban, Hervé Pelloux, R. Hamidfar |
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Přispěvatelé: | Laboratoire Adaptation et pathogénie des micro-organismes [Grenoble] (LAPM), Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF), Laboratoire de Chimie Thérapeutique (UPRES-A CNRS 8076 BIOCIS), Université Paris-Sud - Paris 11 (UP11), Département de médecine aiguë spécialisée, CHU Grenoble-Hôpital Michallon |
Rok vydání: | 2006 |
Předmět: |
Male
Pediatrics Hospitalized patients Consensus criteria Aspergillosis 0302 clinical medicine Epidemiology MESH: Incidence 030212 general & internal medicine Cross Infection 0303 health sciences MESH: Middle Aged Incidence Incidence (epidemiology) General Medicine Middle Aged MESH: Hematologic Diseases 3. Good health Aspergillus Infectious Diseases Population Surveillance MESH: Aspergillus Female France Seasons MESH: Hospital Units Hospital Units Microbiology (medical) medicine.medical_specialty Disease cluster MESH: Population Surveillance Teaching hospital 03 medical and health sciences medicine Humans [SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular Biology MESH: Aspergillosis Hospitals Teaching Intensive care medicine Mycosis MESH: Humans 030306 microbiology business.industry MESH: Cross Infection MESH: Hospitals Teaching medicine.disease Hematologic Diseases MESH: Male MESH: France business MESH: Seasons MESH: Female |
Zdroj: | Journal of Hospital Infection Journal of Hospital Infection, WB Saunders, 2006, 62 (1), pp.22-8. ⟨10.1016/j.jhin.2005.06.013⟩ |
ISSN: | 0195-6701 |
Popis: | A multidisciplinary working group devoted to epidemiological surveillance of invasive aspergillosis (IA) was created in January 2000 in Grenoble University Hospital. This article presents the results of a three-year IA surveillance. The multidisciplinary working group surveyed all hospitalized patients, and the mycology laboratory detected most suspected IA cases. Cases were reviewed monthly by the Aspergillosis Committee, and were classified according to international consensus criteria. Possible nosocomial acquisition was determined. Among the 490 alerts, 74 IA cases were observed: six proven cases (8%), 36 (49%) probable cases and 32 (43%) possible cases. The incidence was 4.4 (95% CI 3.4-5.4) IA/100 000 patient-days. Among the proven and probable IA cases, we observed 10 nosocomial cases and six cases of undetermined origin. No cases were noted in the protected rooms in the haematology unit. Only one cluster of cases (three nosocomial cases) was detected in the haematology unit. Forty-three percent of cases (N=32) were hospitalized in the haematology unit, and all other cases were hospitalized elsewhere. This three-year survey found a high rate of non-nosocomial IA cases and a high frequency of IA cases hospitalized in units other than haematology. Thus, this study shows the importance of IA surveillance in haematology units and all high-risk units. |
Databáze: | OpenAIRE |
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