Caregiver strain in progressive supranuclear palsy and corticobasal syndromes
| Autor: | Lukas Kellermair, Petra Schwingenschuh, Michael Guger, Mariella Kögl, Thomas Forstner, Franz Fellner, Alexandra Fuchs, Stephanie Mangesius, Christian Eggers, Gerhard Ransmayr |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Activities of daily living
Pilot Projects Neurology and Preclinical Neurological Studies - Original Article Caregiver burden Irritability Progressive supranuclear palsy 03 medical and health sciences 0302 clinical medicine Activities of Daily Living medicine Humans Apathy 030212 general & internal medicine Biological Psychiatry Depression (differential diagnoses) business.industry Tinetti test Neuropsychology Syndrome Corticobasal syndrome medicine.disease eye diseases Neuropsychiatric symptoms Caregiver strain Psychiatry and Mental health Caregivers Neurology Female Supranuclear Palsy Progressive Neurology (clinical) medicine.symptom business 030217 neurology & neurosurgery Clinical psychology |
| Zdroj: | Journal of Neural Transmission |
| ISSN: | 1435-1463 0300-9564 |
| Popis: | Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) progress relentlessly and lead to a need for care. Caregiving is often burdensome. Little is known about the course of caregiver burden (CB) in PSP and CBS patients. Longitudinal analysis of CB in family members caring for PSP and CBS patients. Single-center longitudinal pilot study in 68 newly diagnosed patients with probable PSP and CBS (52 Richardson’s syndrome; 1 progressive gait freezing of PSP; 15 CBS). Demographic, educational, occupational parameters, family status, motor functions (UPDRSIII, Hoehn and Yahr Score, Tinetti) and neuropsychological performance (CERAD Plus, Frontal Assessment Battery) were assessed, as well as behavioral and neuropsychiatric impairments (Frontal Behavioral Inventory, Neuropsychiatric Inventory), activities of daily living (ADL) and caregiver burden using the Caregiver Strain Index (CSI), in most patients also the Zarit Burden Interview (ZBI). Patients were followed up every 6 months for up to 2 years. Caregivers reported mild to moderate CB at baseline, which increased by 25–30% in 2 years and was significantly greater in PSP than in CBS. Risk for mental health problems increased over time, especially in female caregivers (depression). Important patient-related factors were apathy, aspontaneity, depression, irritability, disorganization, poor judgment, impairment of language, impairments in ADL, a high educational level of the patient and close family relationship. Behavioral symptoms and impaired ADL are the main patient-related factors of CB in PSP and CBS. CB can be severe and needs to be assessed repeatedly from the time of diagnosis to provide comprehensive support. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink