Middle‐term mortality and re‐bleeding after initial diverticular bleeding: A nationwide study of 365 mostly elderly French patients

Autor: Andre-Jean Remy, Pierre Lahmek, F. Bourhis, René Piperaud, Denis Grasset, B. Bour, Jean-Pierre Arpurt, Stéphane Nahon, Gilbert Bordes, Jacques-Arnaud Seyrig, Bruno Lesgourgues, Claire Gallois, Claire Charpignon, Alexandre Pariente, Gilles Macaigne, Eric Poncin, Roger Faroux, Frédéric Heluwaert, David Bernardini, J. Henrion, Diane Lorenzo, Christine Champion, Chantal Naouri, Magali Picon, Guy Bellaiche
Rok vydání: 2017
Předmět:
Zdroj: United European Gastroenterology Journal. 5:119-127
ISSN: 2050-6414
2050-6406
Popis: The aim of this study was to determine the mortality and re-bleeding rates, and the risk factors involved, in a cohort of patients with previous diverticular bleeding (DB).In 2007, data on 2462 patients with lower gastrointestinal (GI) bleeding were collected prospectively at several French hospitals. We studied the follow-up of patients with DB retrospectively. The following data were collected: age, mortality rates and re-bleeding rates, drug intake, surgery and comorbidities.Data on 365 patients, including 181 women (mean age 83.6 ± 9.8 years) were available. The median follow-up time was 3.9 years (IQR 25-75: 1.7-5.4). Of these, 148 patients died (40.5%). Among the 70 patients (19.2%) who had at least one re-bleeding episode, nine died and three underwent surgical procedures. Anticoagulation and antiplatelet therapy was discontinued in 70 cases (19.2%). The independent risk factors contributing to mortality were age 80 years (HR = 3.18 (2.1-4.9);In this cohort, the rates of mortality and DB re-bleeding after a median follow-up time of 3.9 years were 19.2% and 40.5%, respectively. The majority of the deaths recorded were not due to re-bleeding.
Databáze: OpenAIRE
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