Evaluation of preoperative prediction of intestinal invasion in patients with ovarian cancer

Autor: Shimpei Nagai, Eiichiro Tominaga, Kouji Banno, Shigenori Hayashi, Tatsuya Suzuki, Daisuke Aoki, Yusuke Kobayashi, Shigeo Okuda, Takashi Takeda, Kosuke Tsuji
Rok vydání: 2020
Předmět:
medicine.medical_specialty
Contrast Media
Computed tomography
Carcinoma
Ovarian Epithelial
Sensitivity and Specificity
03 medical and health sciences
Magnetic resonance imaging
0302 clinical medicine
Ovarian cancer
Preoperative Care
medicine
Medical imaging
Humans
Neoplasm Invasiveness
In patient
Intestinal invasion
030212 general & internal medicine
Retrospective Studies
Preoperative
Ovarian Neoplasms
Clinical Article
030219 obstetrics & reproductive medicine
medicine.diagnostic_test
business.industry
Barium contrast radiography
Obstetrics and Gynecology
Cancer
Retrospective cohort study
General Medicine
Middle Aged
medicine.disease
Debulking
Intestines
Radiography
Gynecology
Clinical Articles
Diagnostic imaging
Female
Radiology
Barium Sulfate
Tomography
X-Ray Computed
business
Carcinoma
Endometrioid
Zdroj: International Journal of Gynaecology and Obstetrics
ISSN: 1879-3479
0020-7292
Popis: Objective To optimize prediction for intestinal invasion of epithelial ovarian cancer. It is important to achieve debulking surgery to improve prognosis in ovarian cancer; intestinal resection is adopted if the cancer is invaded and resectable, but the preoperative evaluation method of intestinal invasion is still controversial. Methods Patients (n = 174) who underwent primary debulking surgery for epithelial ovarian cancer were recruited for retrospective study; 28 and 146 patients were classified into the invasion and non‐invasion groups, whether they needed intestinal resection or not. We collected clinical data including evaluation of computed tomography (CT), magnetic resonance imaging (MRI), and barium contrast radiography, and analyzed their accuracy. Results The sensitivity and specificity for intestinal invasion were 33.3% and 98.6%, 42.9% and 98.6%, and 66.7% and 93.9% in CT, MRI, and barium contrast radiography, respectively. CT and MRI combined showed a sensitivity of 58.3% and specificity of 96.9%; all three methods combined was the most sensitive combination, showing a sensitivity of 79.2% and specificity of 90.8%. Conclusion Combination of CT, MRI, and barium contrast radiography predicts intestinal invasion with the highest sensitivity. These three modalities, however, could not predict all intestinal invasion. Patients should be informed of the possibility of unexpected extensive resection.
Synopsis Combination of CT, MRI, and barium contrast radiography give the best prediction of intestinal invasion in ovarian cancer.
Databáze: OpenAIRE
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