Ovarian Strumal Carcinoid Containing Appendiceal-Type Mucinous Tumor Patterns Presenting as Pseudomyxoma Peritonei
Autor: | Francisco F. Nogales, Juan Antonio Retamero, Maolly Schuldt, Enoe Quiñonez |
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Rok vydání: | 2015 |
Předmět: |
endocrine system
Pathology medicine.medical_specialty endocrine system diseases Carcinoid Tumor Biology digestive system Pathology and Forensic Medicine Peritoneal Neoplasm Strumal carcinoid medicine Humans Pseudomyxoma peritonei Peritoneal Neoplasms Ovarian Neoplasms Goblet cell Struma ovarii Obstetrics and Gynecology Foregut Middle Aged Pseudomyxoma Peritonei medicine.disease Adenocarcinoma Mucinous Struma Ovarii medicine.anatomical_structure Adenocarcinoma Female Mucinous Tumor |
Zdroj: | International Journal of Gynecological Pathology. 34:293-297 |
ISSN: | 0277-1691 |
Popis: | We report for the first time a case of ovarian strumal carcinoid containing both trabecular carcinoid and mucinous glands lined by both goblet and neuroendocrine cells and a low-grade mucinous neoplasm that presented clinically as pseudomyxoma peritonei in the absence of appendiceal lesion in a 58-yr-old woman. Histologically, there were both a tall columnar cell epithelial component lacking neuroendocrine cells, showing the scalloped contours and subepithelial clefts of low-grade appendiceal-type neoplasms and a mixed goblet cell neuroendocrine element. Characteristically, both reproduced appendiceal neoplastic phenotypes in a teratoid fashion. In addition, we present previously unreported oncocytic and mucinous changes in the thyroideal components of strumal carcinoid. This case represents a rare instance of pseudomyxoma peritonei of primary ovarian origin and is an example of multiple somatic teratoid endodermal differentiations of the different sections of the embryonal gut: foregut represented by thyroid, midgut by both mucinous appendiceal components, and hindgut by trabecular carcinoid. |
Databáze: | OpenAIRE |
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