Neuroendocrine neoplasms of the extrahepatic bile duct: radiologic and clinical characteristics
| Autor: | So Yeon Kim, Kyoung Won Kim, Seung-Mo Hong, Jae Ho Byun, Hyoung Jung Kim, Nurhee Hong, Jin Hee Kim |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Iohexol Urology Contrast Media Multimodal Imaging Meglumine Bile Ducts Extrahepatic Internal medicine Organometallic Compounds medicine Humans Radiology Nuclear Medicine and imaging Medical history Aged Retrospective Studies Observer Variation Radiological and Ultrasound Technology medicine.diagnostic_test Common bile duct Bile duct business.industry Gastroenterology Magnetic resonance imaging General Medicine Pathology Report Middle Aged Hepatology Image Enhancement Magnetic Resonance Imaging Neuroendocrine Tumors medicine.anatomical_structure Bile Duct Neoplasms Common hepatic duct Positron-Emission Tomography Cystic duct Female Radiology Tomography X-Ray Computed business |
| Zdroj: | Abdominal Imaging. 40:181-191 |
| ISSN: | 1432-0509 0942-8925 |
| DOI: | 10.1007/s00261-014-0191-0 |
| Popis: | To retrospectively identify the radiological and clinical features of neuroendocrine neoplasms of the extrahepatic bile duct. Institutional review board approval was obtained. Between August 2003 and August 2013, 11 patients (range 41–79 years) who had undergone surgery in our institution for neuroendocrine neoplasms of the extrahepatic bile duct were identified. Clinical features (symptoms, laboratory finding, and medical history) were reviewed. A pathologist reviewed the pathology of 11 patients. CT (n = 11), MRI (n = 10), and PET/CT (n = 8) were reviewed by two radiologists in consensus. They were blinded to the clinical features and pathology report. The tumor location was assessed on CT and was classified as occurring in the common hepatic duct, cystic duct, and common bile duct. The tumor shape was assessed in ten patients using MRI and in one patient using CT. The shape was classified as nodular, intraductal-growing, and periductal-infiltrating type. The FDG activity on PET/CT was also evaluated. Correlation of image findings with pathology was made by a radiologist who didn’t participate in the image analysis. There were five men and six women and their median age was 65 years. On pathology examination, seven patients had neuroendocrine carcinoma (64%), three had mixed adenoneuroendocrine carcinoma (27%), and one had neuroendocrine tumor (9%). CT showed that the tumors were located in the common bile duct in seven patients (64%), the common hepatic duct in two (18%), and the cystic duct in two patients (18%). Five tumors were classified as nodular (45%), five as intraductal-growing (45%), and one as periductal-infiltrating type (9%). PET/CT showed increased FDG activity, ranging from 2.7–15.9, in eight patients with neuroendocrine carcinoma. The most common location of neuroendocrine neoplasms of the extrahepatic bile duct is the common bile duct. Most of them are nodular or intraductal-growing type. |
| Databáze: | OpenAIRE |
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