Psoas density – an optimal sarcopaenic indicator associated with postoperative complications after colorectal resection for cancer?
| Autor: | Matej Pekař, Marek Soltes, Tereza Chovancová, Anna Pekařová, Lucia Havrlentová |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
complications Colorectal cancer Urology Computed tomography colorectal cancer 030230 surgery 03 medical and health sciences psoas density 0302 clinical medicine sarcopaenia medicine Rectal resection Single institution Colorectal resection Original Paper medicine.diagnostic_test business.industry Gastroenterology Obstetrics and Gynecology Cancer computed tomography medicine.disease Predictive factor Surgery 030220 oncology & carcinogenesis Cohort Medicine business |
| Zdroj: | Videosurgery and Other Miniinvasive Techniques, Vol 16, Iss 1, Pp 91-97 (2020) Videosurgery and other Miniinvasive Techniques |
| ISSN: | 2299-0054 1895-4588 |
| Popis: | Introduction Sarcopaenia seems to be predictive factor for postoperative morbidity and mortality after colorectal resection for cancer. Nevertheless, an ideal sarcopaenic indicator is still to be identified. Aim To evaluate computed tomography (CT) measured total abdominal muscle area (TAMA), total psoas muscle area (TPA), and psoas density (PD) - previously described sarcopaenia indicators - as possible risk factors for postoperative complications in patients after curative colon and rectal resections for colorectal cancer. Material and methods Consecutive patients after elective curative colon or rectal resection for cancer at a single institution were divided into cohorts with uncomplicated postoperative course or complications Clavien-Dindo grade I-II (Cl-Di 0-II) and complications Clavien-Dindo grade III-V (Cl-Di III-V). Cohorts were statistically tested for significant differences in TAMA, TPA, and PD calculated from preoperative staging CT scans at the level of the third lumbar vertebra. Results Data of 112 patients were analysed from a prospectively run database; 65 underwent colon and 47 rectal resections. PD was significantly higher in the Cl-Di 0-II cohort compared to the Cl-Di III-V for both colon (42.67 ±6.52 vs. 40.11 ±7.57 HU, p = 0.002) and rectal resections (44.08 ±5.86 vs. 43.03 ±5.70HU, p = 0.016). TAMA and TPA failed to show significant differences. Conclusions Psoas density is significantly decreased in patients with Clavien-Dindo grade III-V complications after curative resection for colon and rectal cancer. Due to the simplicity and affordability of its assessment from preoperative staging CT scan, it might be considered an optimal sarcopaenic indicator to be utilised in everyday practice. |
| Databáze: | OpenAIRE |
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