Assessment of changes in endometrial and subendometrial volume and vascularity during the normal menstrual cycle using three-dimensional power Doppler ultrasound

Autor: Lil Valentin, Ligita Jokubkiene, Povilas Sladkevicius, Linas Rovas
Rok vydání: 2006
Předmět:
Zdroj: Ultrasound in Obstetrics & Gynecology; 27(6), pp 672-679 (2006)
ISSN: 1469-0705
0960-7692
DOI: 10.1002/uog.2742
Popis: Objectives To describe changes in endometrial and subendometrial volume and vascularity during the normal menstrual cycle using three-dimensional (3D) power Doppler ultrasonography. Methods Fourteen healthy volunteers, 24–44 years old with regular menstrual cycles, underwent serial transvaginal 3D power Doppler ultrasound examinations of the uterus on cycle day 2, 3 or 4, then daily from cycle day 9 until follicular rupture and 1, 2, 5, 7 and 12 days after follicular rupture. Endometrial and subendometrial volume (cm3), vascularization index (VI), flow index (FI) and vascularization flow index (VFI) were calculated using the VOCAL™ (Virtual Organ Computer-aided AnaLysis) software. Results Endometrial and subendometrial vascularity indices increased throughout the follicular phase, decreased to a nadir 2 days after follicular rupture and then increased again during the luteal phase. Endometrial and subendometrial volume increased rapidly during the follicular phase and then remained almost unchanged during the luteal phase. Conclusions Substantial changes occur in endometrial volume and vascularization during the normal menstrual cycle. There is the potential for 3D power Doppler ultrasonography to become a useful tool for assessing pathological changes associated with female subfertility and abnormal uterine bleeding. Copyright © 2006 ISUOG. Published by John Wiley & Sons, Ltd.
Databáze: OpenAIRE