Daya Antibakteri Kitosan Kepiting Rajungan (Portunus Pelagicus) Terhadap Biofilm Porphyromonas Gingivalis
| Autor: | Laurencia Isabella Loekito, Yoifah Rizka Wedarti, Fani Pangabdian |
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| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | DENTA |
| ISSN: | 2615-1790 1907-5987 |
| DOI: | 10.30649/denta.v12i2.174 |
| Popis: | Background: Porphyromonas gingivalis bacteria are found in dental plaques and have the ability to form biofilms. Biofilms are collections of bacterial cells, which are tightly attached to a surface covered by an extracellular polymer matrix released by the bacteria. Periodontitis therapy generally uses tetracycline antibiotics which if used long-term can cause resistance. Chitosan Rajungan crab extract (Portunus pelagicus) has antimicrobial potential which can be used as an alternative therapy. Objective: To determine the antibacterial power of Rajungan crab chitosan extract (Portunus pelagicus) in various concentrations of Porphyromonas gingivalis bacterial biofilms. Method: This research was true experimental laboratorist . This study used Rajungan crab chitosan extract (Portunus pelagicus) to Porphyromonas gingivalis biofilm tested by the test method biofilm. Divided into 5 groups, where each group consisted of 4 samples. The control group consisted of: K- (negative control group), K + (positive control group / tetracycline group), and 3 treatment groups, namely P1 (0.25% Rajungan crab chitosan), P2 (0.5% Rajungan crab chitosan) , P3 (1% Rajungan crab chitosan). Antibacterial power was determined by the value of Optical density in the ELISA Reader. Data analysis using One Way ANOVA followed by LSD test. Result: There were significant differences (p |
| Databáze: | OpenAIRE |
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