Autor: |
Leonie S. Young, Arnold D. Hill, Peadar Ó Gaora, Paul Tibbitts, Lance Hudson, Marie McIlroy, Jarlath Bolger, Christopher Byrne, Sinéad Cocchiglia, Damir Varešlija, Fiona T. Bane, Damian McCartan, Ailís Fagan, Jean McBryan |
Rok vydání: |
2023 |
Popis: |
Supplementary Figures S1-7. Supplementary Figure S1: Gene expression profiles of classic biomarkers in matched tumour samples from 3 patients. Supplementary Figure S2: Network map showing the enriched KEGG pathways from upregulated differentially expressed genes (DEGs). Supplementary Figure S3: Network map showing the enriched KEGG pathways from downregulated differentially expressed genes (DEGs). Supplementary Figure S4: Protein expression in matched primary and metastatic tissue from endocrine treated breast cancer patients. Supplementary Figure S5: Phosphorylated mTOR signaling in endocrine resistant breast cancer tumours. Supplementary Figure S6: Interaction plot showing functional roles for 21 genes commonly upregulated in metastatic liver tumours of all three patients. Supplementary Figure S7: Genes upregulated in liver metastases are also strongly expressed in breast metastases to the brain. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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