ACROMEGALY AND VITAMIN D METABOLISM: EFFECT OF BROMOCRIPTINE TREATMENT
| Autor: | Bj. Lund, Anthony W. Norman, Ole Helmer Sørensen, Bi. Lund, P. C. Eskildsen, June E. Bishop |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Adult
medicine.medical_specialty Endocrinology Diabetes and Metabolism Clinical Biochemistry Biochemistry Endocrinology Internal medicine Acromegaly medicine Humans Bromocriptine Aged Vitamin D metabolism Hydroxycholecalciferols business.industry Biochemistry (medical) Plasma levels Middle Aged medicine.disease Prolactin Growth Hormone Dihydroxycholecalciferols Calcium business medicine.drug |
| Zdroj: | The Journal of Clinical Endocrinology & Metabolism. 49:484-486 |
| ISSN: | 1945-7197 0021-972X |
| DOI: | 10.1210/jcem-49-3-484 |
| Popis: | Fifteen acromegalic subjects were found to have elevated plasma levels of both 1,25(OH)2-vitamin D, 65 +/- 23 (SD) pg/ml [normal 33 + 15 pg/ml (SD)] and 24,25(OH)2-vitamin D, 6.8 +/- 1.6 (SD) ng/ml [normal 3.4 + 1.2 ng/ml (SD)]. Treatment with bromocriptine for 6 months reduced the plasma 1,25(OH)2-vitamin D3 level to 40 +/- 13 (SD) pg/ml, p less than 0.01 and the 24,25(OH)2-vitamin D level to 5.4 +/- 1.7 (SD) ng/ml, p less than 0.05. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|