Genitourinary manifestations of sickle cell disease
| Autor: | Drogo K. Montague, Surafel Gebreselassie, Matthew N. Simmons |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Male
Pathology medicine.medical_specialty Priapism Kidney Papillary Necrosis Ischemia Anemia Sickle Cell Sickle cell nephropathy Renal medullary carcinoma medicine Humans Kidney Medulla Genitourinary system business.industry Genetic disorder General Medicine medicine.disease Kidney Neoplasms Oxygen tension Female Kidney Diseases business Penis |
| Zdroj: | Cleveland Clinic journal of medicine. 82(10) |
| ISSN: | 1939-2869 |
| Popis: | Sickle cell disease is a common genetic disorder characterized by sickling of red blood cells under conditions of reduced oxygen tension. In turn, sickling leads to intravascular hemolysis and vaso-occlusive events with subsequent tissue ischemia-reperfusion injury affecting multiple organs, including the genitourinary system. Our review of the genitourinary manifestations of sickle cell disease focuses on sickle cell nephropathy, priapism, and other genitourinary complications such as papillary necrosis and renal medullary carcinoma. |
| Databáze: | OpenAIRE |
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