Influence of a skin allograft on frequencies of CTL precursor in peripheral blood of the dog

Autor: R. F. C. Doveren, G. Groenewegen, A. J. J. M. Daemen, Wim A. Buurman, C. J. Van Der Linden, G. Kootstra
Rok vydání: 1984
Předmět:
Zdroj: Transplantation. 38(2)
ISSN: 0041-1337
Popis: Alloantigen-specific cytotoxic T lymphocytes (CTL) and their precursors (CTL-P) have been determined in the peripheral blood of skin allografted dogs. CTL-P frequencies increased rapidly after transplantation and reached maximal values after complete rejection of the skin allograft. Differences in the time response kinetics of CTL-P frequencies between recipients were not correlated with the length of graft survival. The CTL-P frequencies declined after days 13-20 and appeared still to be elevated 30 days after rejection of the graft.
Databáze: OpenAIRE