Adherence to antiretroviral therapy and correlation with adverse effects and coinfections in people living with HIV/AIDS in the municipality of Goiás State
| Autor: | Marcelo Cecílio Daher, Luane da Silva Oliveira, Lorena Maria Caixeta, Rodrigo Scaliante de Moura, Emerith Mayra Hungria Pinto, José Luís Rodrigues Martins, Kelly Deyse Segati |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Microbiology (medical)
Adult Male medicine.medical_specialty Tuberculosis lcsh:Arctic medicine. Tropical medicine Cross-sectional study Anti-HIV Agents lcsh:RC955-962 Coinfections HIV Infections ART adherence Medication Adherence 03 medical and health sciences Young Adult 0302 clinical medicine Acquired immunodeficiency syndrome (AIDS) Internal medicine Surveys and Questionnaires Medicine Humans 030212 general & internal medicine Young adult Adverse effect Aged 030505 public health business.industry Coinfection Adverse effects HIV Middle Aged Viral Load medicine.disease CD4 Lymphocyte Count AIDS Infectious Diseases Cross-Sectional Studies Socioeconomic Factors Parasitology Syphilis Female 0305 other medical science business Viral load |
| Zdroj: | Revista da Sociedade Brasileira de Medicina Tropical, Volume: 51, Issue: 4, Pages: 436-444, Published: AUG 2018 Revista da Sociedade Brasileira de Medicina Tropical, Vol 51, Iss 4, Pp 436-444 Revista da Sociedade Brasileira de Medicina Tropical v.51 n.4 2018 Revista da Sociedade Brasileira de Medicina Tropical Sociedade Brasileira de Medicina Tropical (SBMT) instacron:SBMT |
| Popis: | INTRODUCTION: Acquired immunodeficiency syndrome is an advanced stage of a human immunodeficiency virus infection. The antiretroviral therapy aims to improve the life quality of HIV patients and a good adherence is essential for a better prognosis. This study aimed to evaluate the adherence of human immunodeficiency virus/acquired immunodeficiency syndrome patients to antiretroviral therapy recommended by the Brazilian health system in Anápolis/Goiás, and correlate the level of adherence with sociodemographic data and clinical-laboratory variables. METHODS Adherence to antiretroviral therapy was assessed using the Questionnaire for Evaluation of Adherence to Antiretroviral Therapy. The sociodemographic data were collected using a standardized questionnaire and the clinical-laboratory records were reviewed. RESULTS: Among 220 patients included, 59% (129/220) were men and the average age was 41 years. Infection was acquired primarily through sexual contact (92%, 202/220), and 69% (152/220) of the patients were heterosexual. Approximately 86% (188/220) of the patients had good or strict adherence to antiretroviral therapy. In our study, the use of illicit drugs was associated with low adherence to antiretroviral therapy (p=0.0004), and no significant association was observed between adherence levels and other sociodemographic data (p>0.05). The logistic regression indicated that adverse effects (p=0.0018) and sexual orientation (p=0.0152) were associated with the level of adherence to antiretroviral therapy. Patients with good or strict adherence had higher CD4+T lymphocyte count (p |
| Databáze: | OpenAIRE |
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