Reduction of extracellular superoxide dismutase activity by decapeptide derived from FGF-receptor
| Autor: | Jean Willems, Wim Noppe, Herman Slegers |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
viruses
Molecular Sequence Data Peptide Tripeptide Tumor Cells Cultured Extracellular Animals Humans FGF Receptor Amino Acid Sequence chemistry.chemical_classification biology Superoxide Dismutase virus diseases Glioma Cell Biology General Medicine Cadherins Receptors Fibroblast Growth Factor digestive system diseases Enzyme assay Rats Enzyme chemistry Biochemistry Extracellular superoxide dismutase biology.protein Oligopeptides |
| Zdroj: | Cell biology international |
| ISSN: | 1065-6995 |
| DOI: | 10.1006/cbir.1995.1032 |
| Popis: | Several synthetic decapeptides containing an HAV tripeptide motif were tested for their ability to modulate the enzymatic activity of rat extracellular SOD, an enzyme which also contains an HAV motif. Out of nine decapeptides that were tested, only a FGF-receptor derived peptide was active as a negative modulator of enzyme activity. These results strengthen the thesis that HAV motifs are not only involved in homophilic interactions and suggest that soluble FGF-receptor molecules might moderate the activity of extracellular SOD. |
| Databáze: | OpenAIRE |
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