Prognostic value of left atrial strain in patients with moderate asymptomatic mitral regurgitation
| Autor: | Flavio D'Ascenzi, Matteo Cameli, Mario Stricagnoli, Dan Nistor, S. Sparla, Giulia Elena Mandoli, Francesco Marino, Francesca Maria Righini, Valeria Curci, Sergio Mondillo, Matteo Lisi, Maria Concetta Pastore, Cristina Di Tommaso |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Clinical Decision-Making Mitral surgery timing 030204 cardiovascular system & hematology Asymptomatic Risk Assessment Severity of Illness Index 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Risk Factors Internal medicine Medicine Humans Radiology Nuclear Medicine and imaging 030212 general & internal medicine Myocardial infarction Prospective Studies Stroke Aged Mitral regurgitation Speckle tracking Heart transplantation Observer Variation business.industry Patient Selection Mitral Valve Insufficiency Reproducibility of Results Atrial fibrillation Middle Aged medicine.disease Prognosis Echocardiography Doppler Progression-Free Survival Cardiac surgery Biomechanical Phenomena Heart failure Left atrial dysfunction Asymptomatic Diseases Cardiology Atrial Function Left Female medicine.symptom Cardiology and Cardiovascular Medicine business |
| Popis: | For patients with asymptomatic mitral regurgitation (MR), the criteria identifying the groups at higher-risk and their clinical outcome are still uncertain. Therefore, in these patients, optimal time of surgery remains controversial. The purpose of this study was to compare left atrial (LA) strain to other echocardiographic left ventricular (LV) and LA parameters for the prediction of cardiovascular outcomes in patients with moderate asymptomatic MR. We enrolled 395 patients with primary degenerative moderate asymptomatic MR. Exclusion criteria were: history of atrial fibrillation, myocardial infarction, heart failure, cardiac surgery or heart transplantation, severe MR, mitral valve surgery during follow-up. Patients were prospectively followed for 3.5 ± 1.6 years for the development of cardiovascular events i.e. atrial fibrillation, stroke/transient ischaemic attack, acute heart failure, cardiovascular death. Of 276 patients (mean age 66 ± 8 years) who met eligibility criteria, 108 patients had 141 new events. Patients who developed cardiovascular events presented reduced global peak atrial longitudinal strain (PALS), reduced LA emptying fraction, larger LA volume indexed and lower LV strain at baseline (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|