Clinical profile of uveitis-related ocular hypertension
| Autor: | Tanuj Dada, Sat Pal Garg, Ramanjit Sihota, Deepankur Mahajan, Reetika Sharma, Pradeep Venkatesh |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Intraocular pressure genetic structures Adolescent Glaucoma Ocular hypertension Uveitis Young Adult Risk Factors Ophthalmology medicine Humans Young adult Child Antihypertensive Agents Intraocular Pressure Aged Analysis of Variance business.industry Age Factors Middle Aged medicine.disease eye diseases Logistic Models Corticosteroid use Female Ocular Hypertension Anterior uveitis business Peripheral anterior synechiae |
| Zdroj: | International ophthalmology. 34(6) |
| ISSN: | 1573-2630 |
| Popis: | The purpose of this article is to study the clinical and demographic profile of uveitis-related ocular hypertension (OHT) and evaluate risk factors predisposing to development of OHT in uveitis. Two hundred patients (200 eyes) with uveitis were evaluated for type of uveitis and the presence of OHT [IOP21 mmHg]. All patients underwent a complete ophthalmic examination and appropriate systemic evaluation. Patients with OHT were started on appropriate antiglaucoma medication and were followed up for minimum of 6 months. Forty-two eyes (21 %) were found to have OHT. Anterior uveitis alone was seen in 22 (52.4 %), granulomatous uveitis was seen in 8 (19.1 %) eyes, while 13 eyes (30.9 %) had active uveitis. On multiple logistic regression, age greater than 60 years (p = 0.025), peripheral anterior synechiae (PAS)180° (p = 0.029), and steroid use (p0.001) were found to have significant association with OHT. Mean IOP at baseline was 24.6 ± 10.1 mmHg which decreased to 17.3 ± 4.5 mmHg at 6 months (p0.001). At 6 months, 30 eyes were medically controlled (71.4 %), 5 eyes underwent trabeculectomy with MMC (11.9 %), and in 7 eyes, antiglaucoma medication could be discontinued. One-fifth of eyes with uveitis had OHT. Risk factors for IOP elevation included increased age, PAS180°, and corticosteroid use. |
| Databáze: | OpenAIRE |
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