Renal graft failure after addition of an angiotensin II receptor antagonist to an angiotensin-converting enzyme inhibitor: unmasking of an unknown iliac artery stenosis

Autor: Anne-Lise Kamper, A. H. Nielsen, Svend Just, Niels Bækgaard
Rok vydání: 2002
Předmět:
Zdroj: Journal of the Renin-Angiotensin-Aldosterone System, Vol 3 (2002)
ISSN: 1752-8976
1470-3203
Popis: Combined treatment with an angiotensin-converting enzyme (ACE) inhibitor and an angiotensin II (Ang II) receptor blocker (ARB) has been suggested in order to achieve a more complete blockade of the renin-angiotensin-aldosterone system in cardiovascular and renal disease. The present report describes a case of acute renal graft dysfunction following the addition of an ARB to existing ACE inhibition. This unmasked an unknown iliac artery stenosis. The case indicates a possible important role of Ang II generated by non-ACE pathways in this situation.
Databáze: OpenAIRE