Fatal outcome of pyoderma gangrenosum with multiple organ involvement and partially responding to Infliximab
| Autor: | Gunter Wolf, Carolina Codina Canet, Peter Oelzner, Gert Hein, Martin Kaatz, Stefan Drinda |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
medicine.medical_specialty
Inflammatory dermatosis Fatal outcome business.industry Reproductive medicine General Medicine medicine.disease Dermatology Infliximab Immunology cardiac involvement Etiology Rheumatoid disease Medicine Organ involvement infliximab skin and connective tissue diseases business extracutaneous manifestation Pyoderma gangrenosum pyoderma gangrenosum medicine.drug |
| Zdroj: | Open Medicine, Vol 1, Iss 3, Pp 306-312 (2006) |
| ISSN: | 2391-5463 |
| DOI: | 10.2478/s11536-006-0024-9 |
| Popis: | Pyoderma gangrenosum is an inflammatory dermatosis of uncertain etiology, often associated with chronic inflammatory bowel or rheumatoid disease. It predominantly affects the skin. A systemic organ involvement caused by aseptic neutrophilic abscesses, however, fundamentally influences the prognosis. A patient with idiopathic pyoderma gangrenosum insufficiently responded to a conventional immune suppressive therapy and the disease proceeded aggressively. During treatment with Infliximab, partial remission was achieved intermediately. However, a recurring endocarditis, led to a lethal outcome of this patient. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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