Morphologies and functionalities of polymeric nanocarriers as chemical tools for drug delivery: A review
| Autor: | Iole Venditti |
|---|---|
| Přispěvatelé: | Venditti, Iole |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Drug
Materials science media_common.quotation_subject Drug delivery system Nanoparticle Nanotechnology 02 engineering and technology Polymeric nanocapsule Polymeric nanoparticle 010402 general chemistry 01 natural sciences Nanocapsules Nanomaterials Nanogel Polymeric micelle Dendrimer Nanostructured polymer lcsh:Science (General) media_common Multidisciplinary Vesicle technology industry and agriculture 021001 nanoscience & nanotechnology Controlled release 0104 chemical sciences Drug delivery Nanocarriers 0210 nano-technology lcsh:Q1-390 |
| Zdroj: | Journal of King Saud University: Science, Vol 31, Iss 3, Pp 398-411 (2019) |
| ISSN: | 1018-3647 |
| Popis: | In these years a variety of polymeric nanocarriers such as dendrimers, polymeric micelles, nanoparticles, nanogels, nanocapsules and vesicles are widely investigated as potential drug delivery systems. In addition to the different morphologies and sizes, these carriers may have on their surfaces specific functionalizations to improve the drug loading and controlled release and specific ligands for cell receptors, in order to achieve a precise targeting. This review focuses on recent functionalized polymeric nanomaterials used as drug delivery systems, with an emphasis on morphology and surface modifications of polymeric nanocarriers to improve controlled drug delivery. Moreover, this work offers a number of suggestions on how to achieve the systematization of data on the most relevant physico-chemical parameters, which govern and control the interaction between carrier and drug, with the aim to give the reader an overview of the most significant advances in this field. Keywords: Nanostructured polymers, Drug delivery systems, Dendrimers, polymeric micelles, Polymeric nanoparticles, Nanogels, Polymeric nanocapsules, Vesicles |
| Databáze: | OpenAIRE |
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