Uptake of oxytetracycline, sulfamethoxazole and ketoconazole from fertilised soils by plants
| Autor: | A.A.M. Stolker, Anca Ioana Nicolau, Carmen Lidia Chitescu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Sulfamethoxazole
passive transport Health Toxicology and Mutagenesis Oxytetracycline Toxicology antibiotics BU Dierbehandelingsmiddelen BU Veterinary Drugs Matrix (chemical analysis) Tandem Mass Spectrometry medicine Soil Pollutants plant uptake Fertilizers partition model Chemistry Public Health Environmental and Occupational Health food and beverages General Chemistry General Medicine Plants Soil type Fungicide Watercress Ketoconazole Environmental chemistry Soil water antifungal Chromatography Liquid Food Science medicine.drug |
| Zdroj: | Food Additives and Contaminants-Part A Chemistry, Analysis, Control, Exposure and Risk Assessment 30 (2013) 6 Food Additives and Contaminants-Part A Chemistry, Analysis, Control, Exposure and Risk Assessment, 30(6), 1138-1146 |
| ISSN: | 1944-0049 |
| Popis: | This study was performed to investigate the potential for a set of two antibiotics and one antifungal compound to be taken up from the soil by plants. Plants are used for animal or human consumption, and so the measured concentrations in the plant material will be used to model potential human exposure to these compounds. The uptake by two types of plants (grass and watercress) from two types of soil was studied. The compounds used for these experiments were sulfamethoxazole, oxytetracycline and ketoconazole at concentrations of 5 and 10 mg kg(-1) in the soil. The compounds of interest were extracted out of the plant matrix by applying accelerated solvent extraction. Analyses were carried out by a LC-MS/MS. From the results, it was concluded that the plant materials used for this study were able to take up sulfamethoxazole and ketoconazole when the soil was contaminated with these compounds at a concentration ranging from 5 to 10 mg kg(-1). Sulfamethoxazole was detected in all samples, at levels ranging from 7 to 21 µ kg(-1) for grass and 4 to 7.5 µ kg(-1) for watercress. For ketoconazole, the results showed low absorption. Oxytetracycline was not detected in any sample. A partition-limited model approach was applied for the comparison of experimental and estimated data, and the relationship between physicochemical properties of the compounds and plant uptake was highlighted. |
| Databáze: | OpenAIRE |
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