Liver composition and histology of rainbow trout fed cyclopropenoid fatty acids
| Autor: | D. J. Lee, J.H. Wales, R.O. Sinnhuber, B.J. Struthers |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
Cyclopropanes
medicine.medical_specialty Necrosis Time Factors Trout Clinical Biochemistry Biology Body weight Pathology and Forensic Medicine chemistry.chemical_compound Internal medicine Liver fat medicine Animals Liver histology Molecular Biology Glycogen Body Weight Fatty Acids Histology Organ Size Lipids Endocrinology chemistry Biochemistry Liver Fatty Acids Unsaturated Composition (visual arts) Rainbow trout Bile Ducts medicine.symptom Salmonidae |
| Zdroj: | Experimental and molecular pathology. 23(2) |
| ISSN: | 0014-4800 |
| Popis: | Rainbow trout were fed 200 ppm cyclopropenoid fatty acids (CPFA) in a semipurified casein-gelatin-dextrin diet for 8 months. Liver weights, liver fat, and glycogen levels were measured during the course of the exepriment and compared with those of control fish. The effect of CPFA on liver histology was also monitored and was found to produce necrosis of hepatocytes, unusual glycogen deposition, appearance of “fibers” in the cytoplasm of many cells, and fibrotic bile ducts and blood vessels. Most of these histological abberations remained after MS was removed from the diet. Liver size, expressed as a percentage of body weight, in CPFA-fed fish became significantly larger (P < 0.05) after 7 months and remained higher until the feeding trial was terminated. Percentage of liver lipids was significantly higher (P < 0.05) in CPFA-fed fish, but returned to normal when the fish were returned to control diet. |
| Databáze: | OpenAIRE |
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