Gene regulatory networks mediating cold acclimation: the CBF pathway
| Autor: | Javier Barrero-Gil, Julio Salinas |
|---|---|
| Přispěvatelé: | Ministerio de Economía y Competitividad (España), European Commission, Barrero-Gil, J. [0000-0003-0878-7576], Salinas, Julio [0000-0003-2020-0950], Barrero-Gil, J., Salinas, Julio |
| Rok vydání: | 2018 |
| Předmět: |
0106 biological sciences
0301 basic medicine Regulation of gene expression Signaling integration biology Abiotic stress Gene regulatory network Promoter biology.organism_classification 01 natural sciences Cell biology Gene regulation Light signaling 03 medical and health sciences 030104 developmental biology Arabidopsis Hormone signaling Gene expression Cold acclimation Transcription factors Low temperature Transcription factor 010606 plant biology & botany |
| Zdroj: | Digital.CSIC. Repositorio Institucional del CSIC instname Advances in Experimental Medicine and Biology ISBN: 9789811312434 |
| Popis: | 40 p.-3 fig.-1 tab. Barrero-Gil J., Salinas J. (2018) Gene Regulatory Networks Mediating Cold Acclimation: The CBF Pathway. In: Iwaya-Inoue M., Sakurai M., Uemura M. (eds) Survival Strategies in Extreme Cold and Desiccation. Advances in Experimental Medicine and Biology, vol 1081. Springer, Singapore Under low nonfreezing temperature conditions, plants from temperate climates undergo physiological and biochemical adjustments that increase their tolerance to freezing temperatures. This response, termed cold acclimation, is largely regulated by changes in gene expression. Molecular and genetic studies have identified a small family of transcription factors, called C-repeat binding factors (CBFs), as key regulators of the transcriptomic rearrangement that leads to cold acclimation. The function of these proteins is tightly controlled, and an inadequate supply of CBF activity may be detrimental to the plant. Accumulated evidence has revealed an extremely intricate network of positive and negative regulators of cold acclimation that coalesce at the level of CBF promoters constituting a central hub where multiple internal and external signals are integrated. Moreover, CBF expression is also controlled at posttranscriptional and posttranslational levels further refining CBF regulation. Recently, natural variation studies in Arabidopsis have demonstrated that mutations resulting in changes in CBF expression have an adaptive value for wild populations. Intriguingly, CBF genes are also present in plant species that do not cold acclimate, which suggest that they may also have additional functions. For instance, CBFs are required for some cold-related abiotic stress responses. In addition, their involvement in plant development deserves further study. Although more studies are necessary to fully harness CBF biotechnological potential, these transcription factors are meant to be key for a rational design of crops with enhanced tolerance to abiotic stress. Research in Julio Salinas’s lab is funded by grants BIO2013‐47788‐R from MINECO and BIO2016‐79187‐R from AEI/FEDER, UE. |
| Databáze: | OpenAIRE |
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