Haemodynamic changes measured by transthoracic bioimpedance during treatment with recombinant human erythropoietin
| Autor: | Jones Ma, Paul Sharpstone, J. C. Kingswood, P. Dallyn |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Adult
Male medicine.medical_specialty Physiology Anemia Posture Cardiac index Hemodynamics Blood Pressure Cardiography Impedance Heart Rate Renal Dialysis Internal medicine Internal Medicine medicine Humans Prospective Studies Prospective cohort study Erythropoietin medicine.diagnostic_test business.industry General Medicine Middle Aged medicine.disease Recombinant Proteins Impedance cardiography Endocrinology medicine.anatomical_structure Blood pressure Hypertension Cardiology Vascular resistance Kidney Failure Chronic Female Vascular Resistance sense organs business medicine.drug |
| Zdroj: | Clinical and experimental hypertension (New York, N.Y. : 1993). 18(1) |
| ISSN: | 1064-1963 |
| Popis: | Hypertension complicates the treatment of anaemia of chronic renal failure with recombinant human erythropoietin (EPO) in some patients. We conducted a prospective study measuring changes in cardiac index (CI) and systemic vascular resistance index (SVRI) in 29 patients from before commencement of EPO to attainment of target haemoglobin concentration. We used the operator-independent technique of trans-thoracic bioimpedance. The group of patients who developed EPO-induced hypertension (EpHT) were separately analysed and compared with the group who had no change in blood pressure (NC). Our results showed there was a significant rise in SVRI after treatment in EpHT group patients but in the NC group there was a small fall. CI increased significantly in the NC group after treatment but no change was recorded in the EpHT group. These findings clearly demonstrate how the cardiovascular changes differ in patients who develop EPO-induced hypertension. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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