Prevalence of antibodies to hepatitis C virus in Saudi patients with chronic liver disease
| Autor: | Mohammed Z. Khawaji, Handy O. Ezzat, Yisa M. Fakunle, Abdallah Z. El-Drees, Mohammed Al-Mofarreh, Maria N. Ballesteros, Wafaa M. El-Karamany |
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| Rok vydání: | 1991 |
| Předmět: |
Hepatitis B virus
HBsAg medicine.medical_specialty Cirrhosis biology business.industry Hepatitis C virus Prevalence General Medicine Chronic liver disease medicine.disease medicine.disease_cause Gastroenterology Virology digestive system diseases Hepatocellular carcinoma Internal medicine mental disorders medicine biology.protein Antibody business |
| Zdroj: | Annals of Saudi medicine. 11(5) |
| ISSN: | 0256-4947 |
| Popis: | The prevalence of antibodies to hepatitis C virus (anti-HCV) has been measured in 113 Saudi patients with chronic liver diseases. Twenty-five percent of 20 patients with hepatocellular carcinoma (HCC) were positive for anti-HCV and 29.7% of 38 patients with cirrhosis and 27.3% of 33 patients with liver fibrosis, respectively, also tested positive. The positivity rate for a miscellany of liver diseases (22) was 13.6%. The differences between these prevalence rates were not statistically significant. By comparison, 45% of HCC tested positive for hepatitis B surface antigen (HBsAg) while 52.7% of cirrhosis cases were positive. There rates were statistically significant when compared with HBsAg positivity rates of 9.1% and 18.2% in the liver fibrosis and miscellaneous groups. The role of hepatitis C virus (HCV) may be secondary or additive in the causation of chronic liver disease and hepatocellular carcinoma in this environment in which hepatitis B virus (HBV) is highly endemic. |
| Databáze: | OpenAIRE |
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