Host-targeted therapy for tuberculosis: Time to revisit the concept
| Autor: | Prabha Desikan, Aseem Rangnekar |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Tuberculosis medicine.medical_treatment VEGF receptors Antitubercular Agents lcsh:Medicine Drug resistance Review Article General Biochemistry Genetics and Molecular Biology Targeted therapy 03 medical and health sciences 0302 clinical medicine Tuberculosis Multidrug-Resistant medicine Humans Host-targeted therapy Intensive care medicine biology business.industry lcsh:R Effective management multidrug-resistant/extensively drug-resistant TB General Medicine Mycobacterium tuberculosis medicine.disease Host-targeted therapy - micro RNA - multidrug-resistant/extensively drug-resistant TB - VEGF VEGF Directly Observed Therapy micro RNA Multiple drug resistance 030104 developmental biology Rate of spread 030220 oncology & carcinogenesis biology.protein business |
| Zdroj: | The Indian Journal of Medical Research Indian Journal of Medical Research, Vol 147, Iss 3, Pp 233-238 (2018) |
| ISSN: | 0971-5916 |
| Popis: | Tuberculosis (TB) is an important cause of morbidity and mortality worldwide. Every year millions of people die due to TB. Drug resistance has been a major factor that has obstructed successful control and treatment of TB. As the rate of spread of drug-resistant TB outpaces the rate of discovery of new anti-tubercular drugs, targeted therapy may provide a new approach to TB cure. In a scenario where drug resistance is spreading rapidly, and existing drugs regimens seem to be dwindling away, this review summarizes the concept of host-targeted therapy which may be the ray of hope for the effective management and control of the rapidly spreading drug-resistant TB (multidrug resistant and extensively drug resistant). |
| Databáze: | OpenAIRE |
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