A comparison of demographic, epidemiological and clinical characteristics of hospital influenza-related viral pneumonia patients

Autor:	Lingtong Huang, Ling-Ling Tang, Silan Gu, Bin Fu, Haiting Feng, Qiaomai Xu, Zhengjie Wu, Qinmiao Sun, Peidong Zheng, Zhaohui Chai
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Adult medicine.medical_specialty Microbiological culture Viral pneumonia Pneumonia Viral Infectious and parasitic diseases RC109-216 Influenza B Influenza A Virus H7N9 Subtype Human influenza A Influenza A Virus H1N1 Subtype Pulmonary consolidation Medical microbiology Internal medicine Influenza Human Epidemiology Severe cases medicine Humans Aged Demography Retrospective Studies business.industry Influenza A Virus H3N2 Subtype Middle Aged medicine.disease Hospitals respiratory tract diseases Avian-origin influenza H7N9 Pneumonia Infectious Diseases Sputum medicine.symptom Lymphocytopenia business Research Article
Zdroj:	BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-10 (2021) BMC Infectious Diseases
ISSN:	1471-2334
Popis:	Background Through the comparison of the demographic, epidemiological, and clinical characteristics of hospital human influenza (influenza A (H1N1) pdm09, H3N2, and B)-related and hospitalized avian-origin influenza A (H7N9)-related viral pneumonia patients, find the different between them. Methods A retrospective study was conducted in hospitalized influenza-related viral pneumonia patients. Results Human influenza A-related patients in the 35–49-year-old group were more than those with B pneumonia patients (p = 0.027), and relatively less in the ≥ 65-year-old group than B pneumonia patients (p = 0.079). The proportion of comorbid condition to human influenza A pneumonia was 58%, lower than B pneumonia and H7N9 pneumonia patients (78% vs. 77.8%; p = 0.013). The proportion of invasive mechanical ventilation (IMV), lymphocytopenia, elevated lactate dehydrogenase to hospitalized human influenza A-related viral pneumonia patients was higher than B pneumonia patients (p 10,000/mm3 (OR: 7.22; 95% CI 1.47–35.58; p = 0.015) and positive bacterial culture(blood or sputum) (OR: 6.27; 95% CI 1.36–28.85; p = 0.018) were independently associated with death in the three types hospitalized influenza-related viral pneumonia patients. Conclusions Hospital influenza B-related viral pneumonia mainly affects the elderly and people with underlying diseases, while human influenza A pneumonia mainly affects the young adults; however, the mortality was similar. The hospitalized human influenza A-related viral pneumonia patients was severer than B pneumonia patients, but milder than H7N9 pneumonia patients. Pulmonary consolidation and positive bacterial culture (sputum) were independently associated with IMV, while shock, white blood cell count > 10,000/mm3, and positive bacterial culture (blood or sputum) were independently associated with death to three types hospitalized influenza-related viral pneumonia patients.
Databáze:	OpenAIRE
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