Poly-ε-caprolactone Nanofibrous Polymers: A Simple Alternative to Restricted Access Media for Extraction of Small Molecules from Biological Matrixes
| Autor: | Dalibor Šatínský, Jakub Erben, Jiří Chvojka, Lucie Havlíková, Martina Háková, Frantisek Svec, Petr Solich, Hedvika Raabová |
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| Rok vydání: | 2020 |
| Předmět: |
chemistry.chemical_classification
Polyesters Solid Phase Extraction 010401 analytical chemistry Extraction (chemistry) Nanofibers Proteins Restricted access Polymer Direct transfer 010402 general chemistry 01 natural sciences Small molecule 0104 chemical sciences Analytical Chemistry chemistry.chemical_compound Milk chemistry Chemical engineering Animals Humans Cattle Solid phase extraction Caprolactone |
| Zdroj: | Analytical Chemistry. 92:6801-6805 |
| ISSN: | 1520-6882 0003-2700 |
| DOI: | 10.1021/acs.analchem.0c00544 |
| Popis: | Poly-ε-caprolactone nanofibrous polymer has been used as an alternative to restricted access media for extraction of protein-containing biological samples and direct transfer in the chromatographic system. Three commercial cartridges differing in length and internal diameter have been manually packed with the composite material prepared from poly-ε-caprolactone nanofibers coated on poly-ε-caprolactone microfibrous scaffold and connected to the column-switching chromatographic system. Bovine milk and human serum (25 μL) spiked with a mixture of methyl-, ethyl-, propyl-, and butylparaben in a concentration range of 1-100 μg mL |
| Databáze: | OpenAIRE |
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