Simplified Method for Local Correction of System International Normalized Ratio
| Autor: | Vani Chandrashekar |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Male endocrine system Clinical Biochemistry Thromboplastin 03 medical and health sciences 0302 clinical medicine Elevated pt health services administration Statistics medicine Humans heterocyclic compounds cardiovascular diseases International Normalized Ratio Mathematics Prothrombin time medicine.diagnostic_test fungi Biochemistry (medical) Middle Aged 030104 developmental biology Linear Models Prothrombin Time 030211 gastroenterology & hepatology Female |
| Zdroj: | Laboratory medicine. 48(3) |
| ISSN: | 1943-7730 |
| Popis: | Background International normalized ratio (INR) derivation is dependent on the international sensitivity index (ISI) of thromboplastin. It varies with instrument and reagents used. Objective To evaluate the role of a correction factor in the derivation of INR. Methods We studied prothrombin time (PT) and INR from patients using 3 thromboplastins of varying ISI values. The correction factor was applied to the observed INR to obtain a corrected INR. Results The difference between corrected INR and observed INR values varies from -0.8 through 0.96. Conclusions Corrected INR is dependent on PT only. It can be applied to all patients irrespective of cause for elevated PT. |
| Databáze: | OpenAIRE |
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