Peculiarities of Free-Radical Processes and Neuropsychological Status in Patients with Chronic Generalized Periodontitis and Possibility of Correcting their Impairments with Antioxidant Therapy
| Autor: | Sergej Brankovich Bolevich, Konstantin Sivak, Mihail Petrovich Saulin, Ekaterina Vladimirovna Silina, Tatjana Savateva-Liubiova |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Exacerbation generalized periodontitis Gastroenterology Generalized periodontitis Lipid peroxidation 03 medical and health sciences Basal (phylogenetics) chemistry.chemical_compound 0302 clinical medicine Internal medicine Blood plasma Medicine Periodontitis chemistry.chemical_classification Reactive oxygen species business.industry free radical processes 030206 dentistry General Medicine medicine.disease neuropsychological status 030104 developmental biology chemistry antioxidant therapy Anxiety medicine.symptom business |
| Zdroj: | Serbian Journal of Experimental and Clinical Research, Vol 20, Iss 2, Pp 55-64 (2019) |
| ISSN: | 2335-075X 1820-8665 |
| Popis: | This clinical study included a total of 71 patients with chronic generalized periodontitis (CGP). The chemiluminescence method was used to determine the level of generation of reactive oxygen species by leukocytes (basal and stimulated), as well as the content of malonic dialdehyde in blood plasma and antiperoxide activity of plasma. The anxiety level was measured using the Spielberger’s test. Patients with chronic generalized periodontitis in the exacerbation phase were found to have a natural significant increase in both basal and stimulated PICL, as well as an increase in blood plasma malonic dialdehyde 1.6-, 3.9- and 1.4-fold, respectively, compared with apparently healthy donors (all p |
| Databáze: | OpenAIRE |
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