Two new aspidosperma-type monoterpenoid indole alkaloids from Ervatamia officinalis

Autor:	Bao-Jing Li, Yan Ma, Hai-Shan Qian, Hong-Ping He, Cui-Hong Huang, Guo-Dong Yu, Ben-Qin Tang
Rok vydání:	2022
Předmět:	Pharmacology Complementary and alternative medicine Organic Chemistry Drug Discovery Pharmaceutical Science Molecular Medicine General Medicine Analytical Chemistry
DOI:	10.6084/m9.figshare.20132277
Popis:	Two new aspidosperma-type monoterpenoid indole alkaloids, 16-O-methylvoafinine (1) and 14,15-diepi-voafinidine (2) were isolated from the aerial parts of Ervatamia officinalis. Their structures were established by comprehensive spectroscopic analysis including 1D and 2D NMR, HR-ESI-MS, and electronic circular dichroism calculation. The isolated compounds were evaluated for cytotoxic activities against HepG2, MCF-7, and A549 cell lines by CCK-8 assay.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::badd894c320f92dd04c03f0155a35045 Zobrazit plný text záznamu