Intelligent Wireless EEG Measurement System With Electrical and Optogenetic Stimulation for Epileptic Seizure Detection and Suppression
| Autor: | Shuenn-Yuh Lee, Chieh Tsou, Po-Yen Lu, Zhan-Xian Liao, Chou Ching K. Lin, Gia-Shing Shieh, Tsung-Hsien Lin, Wei-En Lee |
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| Rok vydání: | 2021 |
| Předmět: |
General Computer Science
Computer science education 02 engineering and technology Optogenetics Electroencephalography optical stimulation 03 medical and health sciences 0302 clinical medicine drug-induced seizure 0202 electrical engineering electronic engineering information engineering medicine Electronic engineering Waveform General Materials Science electrical stimulation ChR2 transgene Epilepsy medicine.diagnostic_test 020208 electrical & electronic engineering General Engineering Neurophysiology TK1-9971 wireless EEG measurement system Electrophysiology ComputingMethodologies_PATTERNRECOGNITION Duty cycle Wireless network interface controller Electrical engineering. Electronics. Nuclear engineering Epileptic seizure medicine.symptom 030217 neurology & neurosurgery |
| Zdroj: | IEEE Access, Vol 9, Pp 80264-80274 (2021) |
| ISSN: | 2169-3536 |
| DOI: | 10.1109/access.2021.3083772 |
| Popis: | A two-channel real-time intelligent electroencephalography (EEG) measurement system with electrical and optical stimulations is presented for seizure detection and suppression. Based on software control through a wireless interface, this system provides closed- and open-loop feedback control with programmable waveform for electrical and optical stimulations. Matlab graphical user interface is used to monitor the intracranial EEG, perform the algorithm for seizure detection, and adjust the required intensity, frequency, duty cycle, and duration of electrical and optical stimulations. The whole hardware device is embedded on a printed circuit board with the size of 27.3 mm $\times23.6$ mm. C57BL/6 mice with Thy1-ChR2-YFP gene transfer and drug-induced seizure are used to demonstrate epileptic seizure suppression according to electrical and optogenetic stimulation in the proposed wireless EEG measurement system. |
| Databáze: | OpenAIRE |
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