Testis-specific isoform of angiotensin-converting enzyme (tACE) as a candidate marker for bull fertility

Autor: John P. Kastelic, Jacob C. Thundathil, Mina Ojaghi
Rok vydání: 2017
Předmět:
Zdroj: Reproduction, fertility, and development. 30(11)
ISSN: 1031-3613
Popis: Although a traditional bull breeding soundness evaluation is designed to identify bulls that are grossly abnormal, bulls classified as satisfactory potential breeders still vary in fertility, implying submicroscopic differences in sperm characteristics. Testis-specific isozyme of angiotensin-converting enzyme (tACE) is involved in the regulation of sperm function. Therefore, the aim of the present study was to determine tACE content, activity and localisation in bull spermatozoa and their associations with fertility. Semen from low-fertility (LF) and high-fertility (HF) Holstein bulls (n = 20) with known FERTSOL rates, which represents the 56-day non-return rate, were used. There was greater tACE content (P
Databáze: OpenAIRE