Testis-specific isoform of angiotensin-converting enzyme (tACE) as a candidate marker for bull fertility
Autor: | John P. Kastelic, Jacob C. Thundathil, Mina Ojaghi |
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Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
Male endocrine system animal diseases media_common.quotation_subject Semen Fertility Reproductive technology Peptidyl-Dipeptidase A Isozyme Andrology 03 medical and health sciences fluids and secretions 0302 clinical medicine Endocrinology Testis Genetics Animals Acrosome Molecular Biology reproductive and urinary physiology media_common 030219 obstetrics & reproductive medicine biology urogenital system Angiotensin-converting enzyme Sperm Spermatozoa Enzyme assay 030104 developmental biology Reproductive Medicine biology.protein Sperm Motility Animal Science and Zoology Cattle Developmental Biology Biotechnology |
Zdroj: | Reproduction, fertility, and development. 30(11) |
ISSN: | 1031-3613 |
Popis: | Although a traditional bull breeding soundness evaluation is designed to identify bulls that are grossly abnormal, bulls classified as satisfactory potential breeders still vary in fertility, implying submicroscopic differences in sperm characteristics. Testis-specific isozyme of angiotensin-converting enzyme (tACE) is involved in the regulation of sperm function. Therefore, the aim of the present study was to determine tACE content, activity and localisation in bull spermatozoa and their associations with fertility. Semen from low-fertility (LF) and high-fertility (HF) Holstein bulls (n = 20) with known FERTSOL rates, which represents the 56-day non-return rate, were used. There was greater tACE content (P |
Databáze: | OpenAIRE |
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