The Evaluation of Prognostic Scores in Spontaneous Intracerebral Hemorrhage in an Asian Population: A Retrospective Study
| Autor: | Tseng Tsai Yeo, Arturo Yong Yao Neo, Yi Song Terence Liew, Mervyn Jun Rui Lim, Sein Lwin, Marcus Wei Xuan Tan, Gaurav Deep Singh, Ning Chou, Tharun Ragupathi, Vijay Sharma, Maehanyi Frances Rajendram |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Clinical Decision-Making Risk Assessment 03 medical and health sciences Disability Evaluation 0302 clinical medicine Hematoma Asian People Modified Rankin Scale Predictive Value of Tests Risk Factors Internal medicine Clinical Decision Rules medicine Electronic Health Records Humans Spontaneous intracerebral hemorrhage Aged Cerebral Hemorrhage Retrospective Studies Intracerebral hemorrhage Aged 80 and over Singapore business.industry Medical record Rehabilitation Glasgow Coma Scale Reproducibility of Results Retrospective cohort study Recovery of Function Middle Aged medicine.disease Prognosis Cohort Surgery Female Neurology (clinical) Cardiology and Cardiovascular Medicine business 030217 neurology & neurosurgery |
| Zdroj: | Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 29(12) |
| ISSN: | 1532-8511 |
| Popis: | Objective Clinical grading scales used for prognostication in spontaneous intracerebral hemorrhage facilitate informed-decision making for resource-intensive interventions. Numerous clinical prognostic scores are available for spontaneous intracerebral hemorrhage. However, these have not been validated well in Asian patients, and the most appropriate scoring system remains debatable. We evaluated the utility of clinical scores in prognosticating 30-day mortality and 90-day functional outcome in patients with spontaneous intracerebral hemorrhage. Materials and Methods We conducted a retrospective review of all patients with spontaneous intracerebral hemorrhage admitted to our tertiary center from December 2014 to May 2016. Data on clinical presentation, imaging, and outcomes were extracted from electronic medical records using a standardized form. The data were analyzed for predictors of outcomes. Performance of prognostic scales was compared using receiver-operator characteristic statistics. Results A total of 297 patients were included in the study. Mean age was 60.1 (SD 15.2) years and 190 (64.0%) were male. Thirty-two (10.8%) cases died within 30 days and 177 (62.8%) cases had poor functional outcome (modified Rankin scale of 3 or more) at 90 days. Dialysis dependency (OR=33.54, 95%CI=4.21–325.26, p=0.002), Glasgow coma scale (OR=0.76, 95%CI=0.64–0.88, p=0.001), hematoma volume (OR=1.02, 95%CI=1.00–1.04, p=0.027), and surgical evacuation (OR=0.15, 95%CI=0.02–0.66, p=0.024) were independent predictors for 30-day mortality. The original ICH score (0.862) and the ICH-Grading Scale (0.781) had the highest c-statistic for 30-day mortality and 90-day poor functional outcome respectively. Conclusions Current prognostic scores performed acceptable-to-good in our patient cohort. Future studies may be useful to investigate the utility of these scores in clinical decision-making. |
| Databáze: | OpenAIRE |
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