Coronary artery spasm secondary to carcinoid syndrome
Autor: | Stephen J Fenning, D.E. Newby, Mark W. J. Strachan, C. Toumpanakis |
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Rok vydání: | 2016 |
Předmět: |
Past medical history
Acute coronary syndrome medicine.medical_specialty business.industry Octreotide General Medicine Emergency department 030204 cardiovascular system & hematology medicine.disease Chest pain 03 medical and health sciences 0302 clinical medicine Internal medicine Radionuclide therapy Cardiology Medicine 030212 general & internal medicine medicine.symptom business Carcinoid syndrome Malignant Carcinoid Syndrome medicine.drug |
Zdroj: | QJM : monthly journal of the Association of Physicians. 109(7) |
ISSN: | 1460-2393 |
Popis: | Learning points for clinicians Coronary artery spasm is a rare but important diagnosis to consider in patients with carcinoid syndrome suspected of having an acute coronary syndrome. It can affect patients who do not have pre-existing obstructive arterial disease. This case postulates that radionuclide therapy can be an iatrogenic trigger of carcinoid crisis. A 74-year-old lady was admitted to the emergency department with chest pain and syncope. She was obese and known to have hypertension but was a lifelong non-smoker with no other cardiac risk factors. Her only other significant past medical history was of carcinoid syndrome secondary to a metastatic well-differentiated neuroendocrine tumour of unknown primary. In the three years since her diagnosis, she had become progressively disabled by carcinoid-related symptoms, principally flushing and sweating, and was initially managed with the somatostatin analogue octreotide and … |
Databáze: | OpenAIRE |
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