Coronary artery spasm secondary to carcinoid syndrome

Autor: Stephen J Fenning, D.E. Newby, Mark W. J. Strachan, C. Toumpanakis
Rok vydání: 2016
Předmět:
Zdroj: QJM : monthly journal of the Association of Physicians. 109(7)
ISSN: 1460-2393
Popis: Learning points for clinicians Coronary artery spasm is a rare but important diagnosis to consider in patients with carcinoid syndrome suspected of having an acute coronary syndrome. It can affect patients who do not have pre-existing obstructive arterial disease. This case postulates that radionuclide therapy can be an iatrogenic trigger of carcinoid crisis. A 74-year-old lady was admitted to the emergency department with chest pain and syncope. She was obese and known to have hypertension but was a lifelong non-smoker with no other cardiac risk factors. Her only other significant past medical history was of carcinoid syndrome secondary to a metastatic well-differentiated neuroendocrine tumour of unknown primary. In the three years since her diagnosis, she had become progressively disabled by carcinoid-related symptoms, principally flushing and sweating, and was initially managed with the somatostatin analogue octreotide and …
Databáze: OpenAIRE