Oral surgery in patients under antithrombotic therapy
Autor: | Amanda Leal Rocha, Denise Vieira Travassos, Marina G. Fraga, Daniel Dias Ribeiro, Maria A. Martins, Alessandra Figueiredo de Souza, Ana Cristina Oliveira, Tarcília Aparecida Silva |
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Rok vydání: | 2018 |
Předmět: |
Adult
Male medicine.medical_specialty Oral surgery medicine.drug_class Postoperative Hemorrhage 03 medical and health sciences 0302 clinical medicine Fibrinolytic Agents Risk Factors Antithrombotic medicine Humans In patient Perioperative Period Aged Mouth business.industry Anticoagulant 030206 dentistry Hematology General Medicine Perioperative Middle Aged Oral Hemorrhage Surgery Exact test Regimen 030220 oncology & carcinogenesis Dental surgery Anesthesia Female business |
Zdroj: | Blood Coagulation & Fibrinolysis. 29:97-103 |
ISSN: | 0957-5235 |
Popis: | To investigate perioperative and postoperative bleeding, complications in patients under therapy with anticoagulant or antiplatelet drugs submitted to oral surgery. To evaluate the risk of bleeding and safety for dental surgery, a retrospective chart review was performed. Medical and dental records of patients taking oral antithrombotic drugs undergoing dental surgery between 2010 and 2015 were reviewed. Results were statistically analyzed using Fisher's exact test, t test or the χ test. One hundred and seventy-nine patients underwent 293 surgical procedures. A total of eight cases of perioperative and 12 episodes of postoperative bleeding were documented. The complications were generally managed with local measures and did not require hospitalization. We found significant association of postoperative hemorrhage with increased perioperative bleeding (P = 0.043) and combination of anticoagulant and antiplatelet therapy (P < 0.001). The chance of postoperative hemorrhage for procedures with increased perioperative bleeding is 8.8 times bigger than procedures without perioperative bleeding. Dental surgery in patients under antithrombotic therapy might be carried out without altering the regimen because of low risk of perioperative and postoperative bleeding. However, patients with increased perioperative bleeding should be closely followed up because of postoperative complications risk. |
Databáze: | OpenAIRE |
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