Autor: |
Ae S. Youngpairoj, Thomas H. Vanderford, Matthew S. Reed, Timothy C. Granade, Chou-Pong Pau, Jan Pohl, William M. Switzer, Walid Heneine |
Rok vydání: |
2022 |
Předmět: |
|
Zdroj: |
AIDS (London, England). 36(13) |
ISSN: |
1473-5571 |
Popis: |
Antibody-based testing for emtricitabine (FTC), a critical component of pre-exposure prophylaxis and antiretroviral therapy, would provide low-cost detection for clinical monitoring to improve adherence. We developed a mAb (5D2) to FTC and demonstrated its high specificity and physiologically relevant linear range of detection in a competitive enzyme immunoassay. Thus, this mAb is a key reagent that will enable simple and low-cost lateral flow assays and enzyme immunoassays for adherence monitoring. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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