Dietary supplementation with a nucleotide-rich yeast extract modulates gut immune response and microflora in weaned pigs in response to a sanitary challenge
Autor: | Juan Carlos Rodriguez-Lecompte, F. Yin, Charles M. Nyachoti, Alexander Yitbarek, Rob Patterson, S. M. Waititu |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
gut bacteria Swine Crypt Spleen Ileum Weaning piglets SF1-1100 immune response 03 medical and health sciences Cecum Immune system Animal science Lactobacillus medicine Animals Mesenteric lymph nodes Intestinal Mucosa 2. Zero hunger Meal growth performance biology Interleukin-6 Tumor Necrosis Factor-alpha 0402 animal and dairy science 04 agricultural and veterinary sciences biology.organism_classification Animal Feed 040201 dairy & animal science nucleotides Diet Gastrointestinal Microbiome Interleukin-10 Animal culture 030104 developmental biology medicine.anatomical_structure Dietary Supplements Cytokines Animal Nutritional Physiological Phenomena Animal Science and Zoology Soybeans |
Zdroj: | Animal, Vol 11, Iss 12, Pp 2156-2164 (2017) |
ISSN: | 1751-7311 |
Popis: | An experiment was carried out to evaluate the short-term effect of supplementing a nucleotide-rich yeast extract (NRYE) on growth performance, gut structure, immunity and microflora of piglets raised under sanitary and unsanitary conditions. A total of 84, 21-day old piglets were used in this study; 42 piglets were raised in a room designated as the clean room that was washed once per week, whereas the other 42 piglets were raised in a room designated as the unclean room in which 7 kg of manure from the sow herd was spread on each pen floor on day 1 and 7 and the room was not washed throughout the experiment. The pigs were fed a corn–soybean meal-based diet without or with 0.1% NRYE. Each treatment had 7 replicate pens in each room, and each pen housed 3 pigs. Feed disappearance and BW were recorded on day 1 and 14. On day 14, one pig per pen was euthanized to collect ileum, mesenteric lymph nodes and spleen tissues, and cecum and colon digesta. Overall, NRYE supplementation did not affect growth performance in both clean and unclean conditions, improved kidney weight in both clean (P=0.0002) and unclean room (P |
Databáze: | OpenAIRE |
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