In Silico Hemodynamics and Filtering Evaluation of a Commercial Embolic Protection Device

Autor: A. Gil, Pedro Quintero, Manuel Miralles, Juan Ribera de Serra, Manuel Ignacio Sánchez-Nevárez, Andrea Mares
Rok vydání: 2021
Předmět:
Zdroj: RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname
ANNALS OF BIOMEDICAL ENGINEERING
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
ISSN: 1573-9686
0090-6964
DOI: 10.1007/s10439-021-02846-4
Popis: [EN] During the last years, several kinds of Embolic Protection Devices (EPD) have been developed, with the aim of minimizing complication caused by thrombi generated during Carotid Artery Stenting (CAS). These devices are capable of capturing small particles generated during the intervention, avoiding cerebral stroke and improving the outcomes of the surgery. However, they have associated complications, like the increase on flow resistance associated by their use or the lack of knowledge on their actual filtration efficiency for thrombi of low size. Current work proposes a validated computational methodology in order to predict the hemodynamic features and filtering efficiency of a commercial EPD. It will be observed how Computational Fluid Dynamics predicts pressure drop with fair agreement with the experimental measurements. Finally, this work analyzes the filtration efficiency and the influence of the distribution of injected particles on this parameter. The capabilities of the filter for retaining particles of diameter below the pore size is, additionally, discussed.
This study ws funded by upv-la fe 2020 subprograma proyectos de innovacion (Grant No. DPECFD).
Databáze: OpenAIRE
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