Medição do Óxido Nítrico no Ar Exalado: Utilização na Avaliação de Crianças com História de Sibilância
| Autor: | Iolanda Caires, Pedro Martins, Simões Torres, Joana Valente, Carlos Borrego, José Rosado Pinto, Pedro Lopes da Mata, Nuno Neuparth |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
Spirometry
Male Allergy Pediatrics medicine.medical_specialty Sons Respiratórios medicine.drug_class Population Criança Nitric Oxide Pulmonary function testing Bronchodilator HDE ALER Materials Chemistry medicine Humans Prospective cohort study education Child Asma Asthma Respiratory Sounds lcsh:RC705-779 education.field_of_study Óxido Nítrico medicine.diagnostic_test business.industry lcsh:Diseases of the respiratory system respiratory system medicine.disease respiratory tract diseases Exhalation Exhaled nitric oxide Espirometria Female business |
| Zdroj: | Revista Portuguesa de Pneumologia (English Edition), Vol 14, Iss 2, Pp 195-218 (2008) |
| ISSN: | 2173-5115 |
| Popis: | The body of published work on the role of exhaled nitric oxide (FENO) in the study of bronchial inflammation allows it to be classed as a simple, non-invasive measurement that is very useful in evaluating asthmatic patients.During a prospective study into the effects of air pollution on the health of the population of Viseu (SaudâAR Project), children with a clinical history of wheezing were identified through using the International Study of Asthma and Allergy in Childhood (ISAAC) questionnaire. Children later filled in a new standardised questionnaire and underwent skin-prick-tests, spirometry and FENO measurement. Their mean age was 7.8 ± 1.1 years. Comparing those who wheezed in the 6 months before evaluation (n = 27) with those who didnât, statistical differences for ÎFEV1 (8% median versus 4.5%, p = 0.0399) and for FENO (23 ppb median versus 12 ppb, p = 0.0195, respectively) were observed. Concerning children who needed a bronchodilator in the six previous months (n = 19) and those who didnât, there was also a statistically significant difference in FENO: 27 ppb median versus 11 ppb median, respectively; p |
| Databáze: | OpenAIRE |
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