Simultaneous determination of diphenylhydantoin, mephobarbital, carbamazepine, phenobarbital and primidone in serum using direct chemical ionization mass spectrometry

Autor:	Roger J.W. Truscott, Daniel G. Burke, Roger E. Summons, John Korth, Berthold Halpern
Rok vydání:	1978
Předmět:	Chemical ionization Chromatography Computers Chemistry Mephobarbital Palmitic Acids Carbamazepine Mass Spectrometry Chromatographic separation Evaluation Studies as Topic Phenobarbital Phenytoin Methods medicine Humans Anticonvulsants Routine analysis Primidone Spectroscopy medicine.drug
Zdroj:	Biological Mass Spectrometry. 5:477-482
ISSN:	1096-9888 0306-042X
DOI:	10.1002/bms.1200050803
Popis:	A quantitative method for the simultaneous determination of five anticonvulsants in serum has been developed using chemical ionization mass spectrometry without prior chromatographic separation. The technique was shown to be rapid, simple and sensitive, allowing the routine analysis of 50 microliter of serum with good within-day and day-to-day precision.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9f9a0bc9c55adcd596070170023cf8 https://doi.org/10.1002/bms.1200050803 Zobrazit plný text záznamu Plný text