Fetus-specific serum proteins in several mammals and their relation to human alpha-fetoprotein
| Autor: | Mary Boesman, David Gitlin |
|---|---|
| Rok vydání: | 1967 |
| Předmět: |
Electrophoresis
Primates Research methodology Carnivora Biology Mice Dogs Fetus Antigen Species Specificity Pregnancy Placenta Alpha-Globulins medicine Animals Antigens Immunoelectrophoresis Maternal-Fetal Exchange General Environmental Science Sheep Placentation Embryo Blood Proteins medicine.disease Xenarthra Molecular biology Blood proteins digestive system diseases Rats medicine.anatomical_structure Marsupialia Biochemistry Cats General Earth and Planetary Sciences Cattle Female Rabbits |
| Zdroj: | Comparative biochemistry and physiology. 21(2) |
| ISSN: | 0010-406X |
| Popis: | 1. 1. Fetal and maternal sera from twelve species of mammals were studied electrophoretically and immunochemically for proteins specific for the fetus. 2. 2. In each species, the fetal serum contained an α-globulin not present in maternal serum. 3. 3. The α-fetoproteins of several species had some of the antigenic determinants found in human α-fetoprotein, although antigenic differences among the α-fetoproteins of different species were also apparent; the α-fetoproteins of the species studied appeared to be analogous proteins. 4. 4. Despite the different types of placentation represented, the placenta of each species appeared to be impermeable to α-fetoprotein. |
| Databáze: | OpenAIRE |
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