Risk factors for bronchiolitis hospitalization during the first year of life in a multicenter Italian birth cohort
Autor: | Lanari M, Prinelli F, Adorni F, Di Santo S, Vandini S, Silvestri M, Musicco M, Faldella G, Spinelli M, Corsello G, Gabriele B, La Forgia N, Loprieno S, Boldrini A, Vuerich M, Del Vecchio A, Bertino E, Fabris C, Coscia A, Fanos V, Puddu M, Gargano G, Braibanti S, Corso G, Orfeo L, De Luca MG, Paolillo P, Fabiano A, Barberi I, Arco A, Barboni G, Molinari L, Bonomi A, Ladetto L, Carlucci A, Zorzi G, Dall’Agnola A, Girardi E, Di Fabio S, Faccia P, Bottau P, Macagno F, Ellero S, Magaldi R, Rinaldi M, Memo L, Nicolini G, Ngalikpima CJ, Nosari N, Sarnelli P, Parmigiani S, Agosti M, Negri C, Corona MF, Piano F, Scarcella A, Umbaldo A, De Curtis M, Natale F, Aurilia C, Romagnoli C |
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Přispěvatelé: | Lanari, Marcello, Prinelli, Federica, Adorni, Fulvio, Di Santo, Simona, Vandini, Silvia, Silvestri, Michela, Musicco, Massimo, Lanari M, Prinelli F, Adorni F, Di Santo S, Vandini S, Silvestri M, Musicco M, Faldella G, Spinelli M, Corsello G, Gabriele B, La Forgia N, Loprieno S, Boldrini A, Vuerich M, Del Vecchio A, Bertino E, Fabris C, Coscia A, Fanos V, Puddu M, Gargano G, Braibanti S, Corso G, Orfeo L, De Luca MG, Paolillo P, Fabiano A, Barberi I, Arco A, Barboni G, Molinari L, Bonomi A, Ladetto L, Carlucci A, Zorzi G, Dall’Agnola A, Girardi E, Di Fabio S, Faccia P, Bottau P, Macagno F, Ellero S, Magaldi R, Rinaldi M, Memo L, Nicolini G, Ngalikpima CJ, Nosari N, Sarnelli P, Parmigiani S, Agosti M, Negri C, Corona MF, Piano F, Scarcella A, Umbaldo A, De Curtis M, Natale F, Aurilia C, Romagnoli C |
Jazyk: | angličtina |
Rok vydání: | 2015 |
Předmět: |
Palivizumab
Male Pediatrics medicine.medical_specialty Multivariate analysis Gestational Age Respiratory Syncytial Virus Infections Respiratory syncytial virus Cohort Studies 03 medical and health sciences 0302 clinical medicine Sex Factors Risk Factors 030225 pediatrics medicine Bronchiolitis Viral Humans 030212 general & internal medicine Bronchiolitis Children Hospitalization Prophylaxis Risk factor Breast Feeding Crowding Female Infant Infant Newborn Italy Multivariate Analysis Pediatrics Perinatology and Child Health Viral Bronchiolitis Hospitalization Risk factor Respiratory syncytial virus Prophylaxis Palivizumab Children business.industry Research Gestational age Perinatology and Child Health medicine.disease Newborn 3. Good health Gestation business Breast feeding medicine.drug Cohort study |
Zdroj: | Italian Journal of Pediatrics Italian journal of pediatrics (Online) 41 (2015): 40. doi:10.1186/s13052-015-0149-z info:cnr-pdr/source/autori:Lanari, Marcello; Prinelli, Federica; Adorni, Fulvio; Di Santo, Simona; Vandini, Silvia; Silvestri, Michela; Musicco, Massimo/titolo:Risk factors for bronchiolitis hospitalization during the first year of life in a multicenter Italian birth cohort./doi:10.1186%2Fs13052-015-0149-z/rivista:Italian journal of pediatrics (Online)/anno:2015/pagina_da:40/pagina_a:/intervallo_pagine:40/volume:41 |
DOI: | 10.1186/s13052-015-0149-z |
Popis: | Background: Respiratory Syncytial Virus (RSV) is one of the main causes of respiratory infections during the first year of life. Very premature infants may contract more severe diseases and 'late preterm infants' may also be more susceptible to the infection. The aim of this study is to evaluate the risk factors for hospitalization during the first year of life in children born at different gestational ages in Italy. Methods: A cohort of 33-34 weeks gestational age (wGA) newborns matched by sex and age with two cohort of newborns born at 35-37 wGA and >37 wGA were enrolled in this study for a three-year period (2009-2012). Hospitalization for bronchiolitis (ICD-9 code 466.1) during the first year of life was assessed through phone interview at the end of the RSV season (November-March) and at the completion of the first year of life. Results: The study enrolled 2314 newborns, of which 2210 (95.5 %) had a one year follow-up and were included in the analysis; 120 (5.4 %) were hospitalized during the first year of life for bronchiolitis. Children born at 33-34 wGA had a higher hospitalization rate compared to the two other groups. The multivariate analysis carried out on the entire population associated the following factors with higher rates for bronchiolitis hospitalization: male gender; prenatal treatment with corticosteroids; prenatal exposure to maternal smoking; singleton delivery; respiratory diseases in neonatal period; surfactant therapy; lack of breastfeeding; siblings |
Databáze: | OpenAIRE |
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