Risk factors for bronchiolitis hospitalization during the first year of life in a multicenter Italian birth cohort

Autor: Lanari M, Prinelli F, Adorni F, Di Santo S, Vandini S, Silvestri M, Musicco M, Faldella G, Spinelli M, Corsello G, Gabriele B, La Forgia N, Loprieno S, Boldrini A, Vuerich M, Del Vecchio A, Bertino E, Fabris C, Coscia A, Fanos V, Puddu M, Gargano G, Braibanti S, Corso G, Orfeo L, De Luca MG, Paolillo P, Fabiano A, Barberi I, Arco A, Barboni G, Molinari L, Bonomi A, Ladetto L, Carlucci A, Zorzi G, Dall’Agnola A, Girardi E, Di Fabio S, Faccia P, Bottau P, Macagno F, Ellero S, Magaldi R, Rinaldi M, Memo L, Nicolini G, Ngalikpima CJ, Nosari N, Sarnelli P, Parmigiani S, Agosti M, Negri C, Corona MF, Piano F, Scarcella A, Umbaldo A, De Curtis M, Natale F, Aurilia C, Romagnoli C
Přispěvatelé: Lanari, Marcello, Prinelli, Federica, Adorni, Fulvio, Di Santo, Simona, Vandini, Silvia, Silvestri, Michela, Musicco, Massimo, Lanari M, Prinelli F, Adorni F, Di Santo S, Vandini S, Silvestri M, Musicco M, Faldella G, Spinelli M, Corsello G, Gabriele B, La Forgia N, Loprieno S, Boldrini A, Vuerich M, Del Vecchio A, Bertino E, Fabris C, Coscia A, Fanos V, Puddu M, Gargano G, Braibanti S, Corso G, Orfeo L, De Luca MG, Paolillo P, Fabiano A, Barberi I, Arco A, Barboni G, Molinari L, Bonomi A, Ladetto L, Carlucci A, Zorzi G, Dall’Agnola A, Girardi E, Di Fabio S, Faccia P, Bottau P, Macagno F, Ellero S, Magaldi R, Rinaldi M, Memo L, Nicolini G, Ngalikpima CJ, Nosari N, Sarnelli P, Parmigiani S, Agosti M, Negri C, Corona MF, Piano F, Scarcella A, Umbaldo A, De Curtis M, Natale F, Aurilia C, Romagnoli C
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Palivizumab
Male
Pediatrics
medicine.medical_specialty
Multivariate analysis
Gestational Age
Respiratory Syncytial Virus Infections
Respiratory syncytial virus
Cohort Studies
03 medical and health sciences
0302 clinical medicine
Sex Factors
Risk Factors
030225 pediatrics
medicine
Bronchiolitis
Viral

Humans
030212 general & internal medicine
Bronchiolitis
Children
Hospitalization
Prophylaxis
Risk factor
Breast Feeding
Crowding
Female
Infant
Infant
Newborn

Italy
Multivariate Analysis
Pediatrics
Perinatology and Child Health

Viral
Bronchiolitis
Hospitalization
Risk factor
Respiratory syncytial virus
Prophylaxis
Palivizumab
Children

business.industry
Research
Gestational age
Perinatology and Child Health
medicine.disease
Newborn
3. Good health
Gestation
business
Breast feeding
medicine.drug
Cohort study
Zdroj: Italian Journal of Pediatrics
Italian journal of pediatrics (Online) 41 (2015): 40. doi:10.1186/s13052-015-0149-z
info:cnr-pdr/source/autori:Lanari, Marcello; Prinelli, Federica; Adorni, Fulvio; Di Santo, Simona; Vandini, Silvia; Silvestri, Michela; Musicco, Massimo/titolo:Risk factors for bronchiolitis hospitalization during the first year of life in a multicenter Italian birth cohort./doi:10.1186%2Fs13052-015-0149-z/rivista:Italian journal of pediatrics (Online)/anno:2015/pagina_da:40/pagina_a:/intervallo_pagine:40/volume:41
DOI: 10.1186/s13052-015-0149-z
Popis: Background: Respiratory Syncytial Virus (RSV) is one of the main causes of respiratory infections during the first year of life. Very premature infants may contract more severe diseases and 'late preterm infants' may also be more susceptible to the infection. The aim of this study is to evaluate the risk factors for hospitalization during the first year of life in children born at different gestational ages in Italy. Methods: A cohort of 33-34 weeks gestational age (wGA) newborns matched by sex and age with two cohort of newborns born at 35-37 wGA and >37 wGA were enrolled in this study for a three-year period (2009-2012). Hospitalization for bronchiolitis (ICD-9 code 466.1) during the first year of life was assessed through phone interview at the end of the RSV season (November-March) and at the completion of the first year of life. Results: The study enrolled 2314 newborns, of which 2210 (95.5 %) had a one year follow-up and were included in the analysis; 120 (5.4 %) were hospitalized during the first year of life for bronchiolitis. Children born at 33-34 wGA had a higher hospitalization rate compared to the two other groups. The multivariate analysis carried out on the entire population associated the following factors with higher rates for bronchiolitis hospitalization: male gender; prenatal treatment with corticosteroids; prenatal exposure to maternal smoking; singleton delivery; respiratory diseases in neonatal period; surfactant therapy; lack of breastfeeding; siblings
Databáze: OpenAIRE