Urinary tract infection due toAchromobacter xylosoxidans: Report of 9 cases
| Autor: | Oliva Sancho, Alejandro González-Praetorius, Julia Bisquert, Mercedes Pérez-Balsalobre, Daniel Tena |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Male Microbiology (medical) medicine.medical_specialty Asymptomatic Cohort Studies Immunocompromised Host Drug Resistance Multiple Bacterial Neoplasms Internal medicine Ampicillin medicine Humans Urinary Tract Aged Retrospective Studies General Immunology and Microbiology biology business.industry Achromobacter denitrificans General Medicine Achromobacter xylosoxidans Middle Aged Amoxicillin bacterial infections and mycoses biology.organism_classification Surgery Ciprofloxacin Infectious Diseases Nitrofurantoin Urinary Tract Infections Female medicine.symptom Gram-Negative Bacterial Infections business Cefuroxime medicine.drug |
| Zdroj: | Scandinavian Journal of Infectious Diseases. 40:84-87 |
| ISSN: | 1651-1980 0036-5548 |
| DOI: | 10.1080/00365540701558714 |
| Popis: | Urinary tract infection (UTI) due to Achromobacter xylosoxidans is rare. The aims were to know the frequency and clinical characteristics of this infection in our area. We performed a retrospective analysis of 9 patients with UTI caused by this organism diagnosed over a period of 13 y. The mean age was 63.1 y. All patients had underlying diseases or urological abnormalities. The most frequent underlying diseases were solid or hematological malignancies (3 cases). Seven patients (77.7%) had urological abnormalities. Eight patients had symptoms of cystitis and 1 remained asymptomatic. Seven patients had community acquired UTIs. Clinical outcome was favourable in 5 patients after antibiotic treatment and recurrence occurred in 3 patients who had urological abnormalities. All isolates were susceptible to imipenem and piperacillin-tazobactam, 88.8% were susceptible to ceftazidime and 77.7% were susceptible to trimethoprim-sulfamethoxazole. High frequencies of resistance to ampicillin (100%), amoxicillin/clavulanic acid (78%), cefuroxime (100%), cefotaxime (67%), norfloxacin (89%), ciprofloxacin (78%), nitrofurantoin (89%) and gentamicin (67%) were observed. UTI due to A. xylosoxidans was predominantly observed in elderly patients with predisposing factors, especially urological abnormalities, malignancies and immunosuppression. Treatment can be difficult due to the high level of antibiotic resistance. Trimethoprim-sulfamethoxazole may be useful for treatment, particularly in outpatients with community acquired infections. |
| Databáze: | OpenAIRE |
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