A current review of pathogenicity determinants of Streptococcus sp
Autor: | Pamella Silva Lannes-Costa, G da Silva Santos, J S S de Oliveira, Prescilla Emy Nagao |
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Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
Virulence Factors Virulence Applied Microbiology and Biotechnology Microbiology 03 medical and health sciences Immune system Streptococcal Infections Molecular genetics medicine Animals Humans Phylogeny 030304 developmental biology Infectivity 0303 health sciences biology 030306 microbiology Mechanism (biology) Host (biology) Biofilm Streptococcus General Medicine biology.organism_classification Bacteria Biotechnology |
Zdroj: | Journal of Applied Microbiology. 131:1600-1620 |
ISSN: | 1365-2672 1364-5072 |
Popis: | The genus Streptococcus comprises important pathogens, many of them are part of the human or animal microbiota. Advances in molecular genetics, taxonomic approaches and phylogenomic studies have led to the establishment of at least 100 species that have a severe impact on human health and are responsible for substantial economic losses to agriculture. The infectivity of the pathogens is linked to cell-surface components and/or secreted virulence factors. Bacteria have evolved sophisticated and multifaceted adaptation strategies to the host environment, including biofilm formation, survival within professional phagocytes, escape the host immune response, amongst others. This review focuses on virulence mechanism and zoonotic potential of Streptococcus species from pyogenic (S. agalactiae, S. pyogenes) and mitis groups (S. pneumoniae). |
Databáze: | OpenAIRE |
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